Prostate tumor progression is mediated by a paracrine TGF-beta/Wnt3a signaling axis. - Wikidata - wikimedia - TriplyDB

Prostate tumor progression is mediated by a paracrine TGF-beta/Wnt3a signaling axis.

Prostate tumor progression is mediated by a paracrine TGF-beta/Wnt3a signaling axis.

http://www.wikidata.org/entity/Q39305976

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Development of anticancer agents targeting the Wnt/β-catenin signaling The many ways to make a luminal cell and a prostate cancer cell Multifocal epithelial tumors and field cancerization: stroma as a primary determinant Understanding the role of stromal fibroblasts in cancer progression Wnt/β-catenin signalling in prostate cancer Prostate cancer progression and metastasis: potential regulatory pathways for therapeutic targeting.Cancer associated fibroblasts in cancer pathogenesis Bone marrow derived mesenchymal stem cells incorporate into the prostate during regrowth.Prostate cancer and bone: the elective affinities.Essential roles of epithelial bone morphogenetic protein signaling during prostatic development.Effects of androgen receptor and androgen on gene expression in prostate stromal fibroblasts and paracrine signaling to prostate cancer cells Mouse models of prostate cancer: picking the best model for the question.Prostate cancer regulatory networks A reciprocal role of prostate cancer on stromal DNA damage.STAT3 upregulates the protein expression and transcriptional activity of β-catenin in breast cancer.Epithelial Hic-5/ARA55 expression contributes to prostate tumorigenesis and castrate responsiveness.Bone Metastasis of Prostate Cancer Can Be Therapeutically Targeted at the TBX2-WNT Signaling Axis.Inflammation-mediated genetic and epigenetic alterations drive cancer development in the neighboring epithelium upon stromal abrogation of TGF-β signaling.Inflammation and pyroptosis mediate muscle expansion in an interleukin-1β (IL-1β)-dependent manner Inactivation of AR/TMPRSS2-ERG/Wnt signaling networks attenuates the aggressive behavior of prostate cancer cells.Can we safely target the WNT pathway?High mammographic density is associated with an increase in stromal collagen and immune cells within the mammary epithelium.Targeting Notch, Hedgehog, and Wnt pathways in cancer stem cells: clinical update Wnt3a: functions and implications in cancer.High Caveolin-1 Expression in Tumor Stroma Is Associated with a Favourable Outcome in Prostate Cancer Patients Managed by Watchful Waiting Sabutoclax, a Mcl-1 antagonist, inhibits tumorigenesis in transgenic mouse and human xenograft models of prostate cancer Targeted delivery of paclitaxel to EphA2-expressing cancer cells The evolving roles of canonical WNT signaling in stem cells and tumorigenesis: implications in targeted cancer therapies Integrated gene and miRNA expression analysis of prostate cancer associated fibroblasts supports a prominent role for interleukin-6 in fibroblast activation The stroma-a key regulator in prostate function and malignancy Inorganic Arsenic-Related Changes in the Stromal Tumor Microenvironment in a Prostate Cancer Cell-Conditioned Media Model.Mesenchymal stroma: primary determinant and therapeutic target for epithelial cancer.Loss of TGF-β responsiveness in prostate stromal cells alters chemokine levels and facilitates the development of mixed osteoblastic/osteolytic bone lesions.FGFR1-WNT-TGF-β signaling in prostate cancer mouse models recapitulates human reactive stroma.Genes upregulated in prostate cancer reactive stroma promote prostate cancer progression in vivo.Expression of the Y-Encoded TSPY is Associated with Progression of Prostate Cancer.A novel highly potent trivalent TGF-β receptor trap inhibits early-stage tumorigenesis and tumor cell invasion in murine Pten-deficient prostate glands.The reactive stroma microenvironment and prostate cancer progression.Cell mates: paracrine and stromal targets for prostate cancer therapy.The Multifaceted Roles of STAT3 Signaling in the Progression of Prostate Cancer.

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Prostate tumor progression is mediated by a paracrine TGF-beta/Wnt3a signaling axis.

http://www.wikidata.org/entity/Q39305976

description

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name

Prostate tumor progression is mediated by a paracrine TGF-beta/Wnt3a signaling axis.

@en

Prostate tumor progression is mediated by a paracrine TGF-beta/Wnt3a signaling axis.

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type

label

Prostate tumor progression is mediated by a paracrine TGF-beta/Wnt3a signaling axis.

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Prostate tumor progression is mediated by a paracrine TGF-beta/Wnt3a signaling axis.

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prefLabel

Prostate tumor progression is mediated by a paracrine TGF-beta/Wnt3a signaling axis.

@en

Prostate tumor progression is mediated by a paracrine TGF-beta/Wnt3a signaling axis.

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Identification of c-MYC as a target of the APC pathway

Role of p14ARF in TWIST-mediated senescence in prostate epithelial cells

The glucocorticoid receptor inhibits NFkappaB by interfering with serine-2 phosphorylation of the RNA polymerase II carboxy-terminal domain

Wnt/beta-catenin signaling in development and disease

Mechanisms of TGF-beta signaling from cell membrane to the nucleus

beta-catenin signaling and cancer

Role of p63 and basal cells in the prostate

Many tumors induced by the mouse mammary tumor virus contain a provirus integrated in the same region of the host genome

Stromal fibroblasts in cancer initiation and progression

TGF-beta signaling in fibroblasts modulates the oncogenic potential of adjacent epithelia

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