Targeting a pre-mRNA structure with bipartite antisense molecules modulates tau alternative splicing.
about
The role of tau in neurodegenerative diseases and its potential as a therapeutic targetAntisense oligonucleotides: treating neurodegeneration at the level of RNATargeting mRNA for Alzheimer's and related dementias.The Role of MAPT in Neurodegenerative Diseases: Genetics, Mechanisms and TherapyAmetantrone-based compounds as potential regulators of Tau pre-mRNA alternative splicing.Identification of a Peptide for Systemic Brain Delivery of a Morpholino Oligonucleotide in Mouse Models of Spinal Muscular AtrophyTemplate-directed synthesis of a small molecule-antisense conjugate targeting an mRNA structure.Targeting RNA splicing for disease therapy.Splice-switching antisense oligonucleotides as therapeutic drugsExon-skipping antisense oligonucleotides to correct missplicing in neurogenetic diseases.Development of therapeutic splice-switching oligonucleotides.RNA triplexes: from structural principles to biological and biotech applications.Invited review: Drug development for tauopathies.Trans-splicing correction of tau isoform imbalance in a mouse model of tau mis-splicing.Emerging Diagnostic and Therapeutic Strategies for Tauopathies.Sequence-specific and Selective Recognition of Double-stranded RNAs over Single-stranded RNAs by Chemically Modified Peptide Nucleic Acids.Nucleic Acid-Based Theranostics for Tackling Alzheimer's Disease.
P2860
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P2860
Targeting a pre-mRNA structure with bipartite antisense molecules modulates tau alternative splicing.
description
2012 nî lūn-bûn
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2012年の論文
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name
Targeting a pre-mRNA structure ...... ates tau alternative splicing.
@en
Targeting a pre-mRNA structure ...... ates tau alternative splicing.
@nl
type
label
Targeting a pre-mRNA structure ...... ates tau alternative splicing.
@en
Targeting a pre-mRNA structure ...... ates tau alternative splicing.
@nl
prefLabel
Targeting a pre-mRNA structure ...... ates tau alternative splicing.
@en
Targeting a pre-mRNA structure ...... ates tau alternative splicing.
@nl
P2093
P2860
P356
P1476
Targeting a pre-mRNA structure ...... ates tau alternative splicing.
@en
P2093
Eleanor Peacey
Lilia Rodriguez
Michael S Wolfe
P2860
P304
P356
10.1093/NAR/GKS710
P407
P577
2012-07-25T00:00:00Z