Double-stranded RNA binding of influenza B virus nonstructural NS1 protein inhibits protein kinase R but is not essential to antagonize production of alpha/beta interferon.
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Influenza B virus ribonucleoprotein is a potent activator of the antiviral kinase PKRNegative regulation of cytoplasmic RNA-mediated antiviral signalingConserved surface features form the double-stranded RNA binding site of non-structural protein 1 (NS1) from influenza A and B virusesReplication-competent fluorescent-expressing influenza B virusInnate immune evasion strategies of influenza virusesTipping the balance: antagonism of PKR kinase and ADAR1 deaminase functions by virus gene products.Influenza B virus NS1-truncated mutants: live-attenuated vaccine approach.Functional analysis of the short isoform of orf virus protein OV20.0.Incoming influenza A virus evades early host recognition, while influenza B virus induces interferon expression directly upon entry.Analysis of influenza B Virus NS1 protein trafficking reveals a novel interaction with nuclear speckle domainsTRBP control of PACT-induced phosphorylation of protein kinase R is reversed by stress.Robust Lys63-Linked Ubiquitination of RIG-I Promotes Cytokine Eruption in Early Influenza B Virus Infection.Sabotage of antiviral signaling and effectors by influenza viruses.Molecular and biochemical characterization of the NS1 protein of non-cultured influenza B virus strains circulating in Singapore.Mitochondrion: an emerging platform critical for host antiviral signaling.Activation of the Antiviral Kinase PKR and Viral Countermeasures.Innate immunity to influenza in chronic airways diseases.Influenza A Virus Virulence Depends on Two Amino Acids in the N-Terminal Domain of Its NS1 Protein To Facilitate Inhibition of the RNA-Dependent Protein Kinase PKR.Limited compatibility of polymerase subunit interactions in influenza A and B viruses.The TAK1-JNK cascade is required for IRF3 function in the innate immune response.Phosphorylation of IRF-3 on Ser 339 generates a hyperactive form of IRF-3 through regulation of dimerization and CBP association.Human interactome of the influenza B virus NS1 protein.A Second RNA-Binding Site in the NS1 Protein of Influenza B Virus.Mice lacking the ISG15 E1 enzyme UbE1L demonstrate increased susceptibility to both mouse-adapted and non-mouse-adapted influenza B virus infection.Activation of phosphatidylinositol 3-kinase signaling by the nonstructural NS1 protein is not conserved among type A and B influenza viruses.Host Cell Restriction Factors that Limit Influenza A Infection.Influenza Virus: A Master Tactician in Innate Immune Evasion and Novel Therapeutic Interventions.Role of the influenza virus nonstructural 1 protein in evasion of immunityThe RNA Helicase DDX6 Associates with RIG-I to Augment Induction of Antiviral Signaling
P2860
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P2860
Double-stranded RNA binding of influenza B virus nonstructural NS1 protein inhibits protein kinase R but is not essential to antagonize production of alpha/beta interferon.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh
2006年學術文章
@zh-hant
name
Double-stranded RNA binding of ...... tion of alpha/beta interferon.
@en
Double-stranded RNA binding of ...... tion of alpha/beta interferon.
@nl
type
label
Double-stranded RNA binding of ...... tion of alpha/beta interferon.
@en
Double-stranded RNA binding of ...... tion of alpha/beta interferon.
@nl
prefLabel
Double-stranded RNA binding of ...... tion of alpha/beta interferon.
@en
Double-stranded RNA binding of ...... tion of alpha/beta interferon.
@nl
P2093
P2860
P356
P1433
P1476
Double-stranded RNA binding of ...... tion of alpha/beta interferon.
@en
P2093
Bianca Dauber
Jana Schneider
Thorsten Wolff
P2860
P304
11667-11677
P356
10.1128/JVI.01142-06
P407
P577
2006-09-20T00:00:00Z