Non-coplanar polychlorinated biphenyls (PCBs) are direct agonists for the human pregnane-X receptor and constitutive androstane receptor, and activate target gene expression in a tissue-specific manner.
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Retinoid-xenobiotic interactions: the Ying and the YangToxicant-associated steatohepatitisPolychlorinated biphenyls and links to cardiovascular diseaseHuman receptor activation by aroclor 1260, a polychlorinated biphenyl mixtureEvaluation of Aroclor 1260 exposure in a mouse model of diet-induced obesity and non-alcoholic fatty liver diseaseLiver transcriptome analysis of Atlantic cod (Gadus morhua) exposed to PCB 153 indicates effects on cell cycle regulation and lipid metabolismLack of data drives uncertainty in PCB health risk assessments.TLR4 signaling is involved in brain vascular toxicity of PCB153 bound to nanoparticles.Regulation of pregnane-X-receptor, CYP3A and P-glycoprotein genes in the PCB-resistant killifish (Fundulus heteroclitus) population from New Bedford Harbor.Biomonitoring of non-dioxin-like polychlorinated biphenyls in transgenic Arabidopsis using the mammalian pregnane X receptor system: a role of pectin in pollutant uptakeEnvironmental contaminants activate human and polar bear (Ursus maritimus) pregnane X receptors (PXR, NR1I2) differentlyInfluence of Low-Level Prenatal Exposure to PCDD/Fs and PCBs on Empathizing, Systemizing and Autistic Traits: Results from the Duisburg Birth Cohort Study.Lipopolysaccharide potentiates polychlorinated biphenyl-induced disruption of the blood-brain barrier via TLR4/IRF-3 signalingPolychlorinated biphenyl 153 is a diet-dependent obesogen that worsens nonalcoholic fatty liver disease in male C57BL6/J mice.Characterizing drug-metabolizing enzymes and transporters that are bona fide CAR-target genes in mouse intestineThe Role of MicroRNAs in Environmental Risk Factors, Noise-Induced Hearing Loss, and Mental Stress.Mechanisms of xenobiotic receptor activation: Direct vs. indirect.Nuclear receptors and nonalcoholic fatty liver disease.Activating nuclear xenobiotic receptors and triggering ER stress and hepatic cytochromes P450 systems in quails (Coturnix C. coturnix) during atrazine exposure.Low-Chlorinated Non-Dioxin-like Polychlorinated Biphenyls Present in Blood and Breast Milk Induce Higher Levels of Reactive Oxygen Species in Neutrophil Granulocytes than High-Chlorinated Congeners.Epigenetic impact of endocrine disrupting chemicals on lipid homeostasis and atherosclerosis: a pregnane X receptor-centric view.Polychlorinated biphenyls disrupt hepatic epidermal growth factor receptor signaling.A structure-activity relationship linking non-planar PCBs to functional deficits of neural crest cells: new roles for connexins.Editor's Highlight: PCB126 Exposure Increases Risk for Peripheral Vascular Diseases in a Liver Injury Mouse Model.Intestinal exposure to PCB 153 induces inflammation via the ATM/NEMO pathway.Atropisomers of 2,2',3,3',6,6'-hexachlorobiphenyl (PCB 136) exhibit stereoselective effects on activation of nuclear receptors in vitro.Mechanisms of Action Point Towards Combined PBDE/NDL-PCB Risk Assessment.In vitro profiling of toxic effects of prominent environmental lower-chlorinated PCB congeners linked with endocrine disruption and tumor promotion.In Vitro Cocktail Effects of PCB-DL (PCB118) and Bulky PCB (PCB153) with BaP on Adipogenesis and on Expression of Genes Involved in the Establishment of a Pro-Inflammatory State.Assessing Binary Mixture Effects from Genotoxic and Endocrine Disrupting Environmental Contaminants Using Infrared Spectroscopy
P2860
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P2860
Non-coplanar polychlorinated biphenyls (PCBs) are direct agonists for the human pregnane-X receptor and constitutive androstane receptor, and activate target gene expression in a tissue-specific manner.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
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2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
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2012年學術文章
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name
Non-coplanar polychlorinated b ...... n in a tissue-specific manner.
@en
Non-coplanar polychlorinated b ...... n in a tissue-specific manner.
@en-gb
Non-coplanar polychlorinated b ...... n in a tissue-specific manner.
@nl
type
label
Non-coplanar polychlorinated b ...... n in a tissue-specific manner.
@en
Non-coplanar polychlorinated b ...... n in a tissue-specific manner.
@en-gb
Non-coplanar polychlorinated b ...... n in a tissue-specific manner.
@nl
prefLabel
Non-coplanar polychlorinated b ...... n in a tissue-specific manner.
@en
Non-coplanar polychlorinated b ...... n in a tissue-specific manner.
@en-gb
Non-coplanar polychlorinated b ...... n in a tissue-specific manner.
@nl
P1476
Non-coplanar polychlorinated b ...... n in a tissue-specific manner.
@en
P2093
Fadheela Al-Salman
P356
10.1016/J.TAAP.2012.05.016
P50
P577
2012-06-01T00:00:00Z