Primary HIV-1 infection of human CD4+ T cells passaged into SCID mice leads to selection of chronically infected cells through a massive fas-mediated autocrine suicide of uninfected cells.
about
Human immunodeficiency virus type 1 strains R5 and X4 induce different pathogenic effects in hu-PBL-SCID mice, depending on the state of activation/differentiation of human target cells at the time of primary infection.Binding of human immunodeficiency virus type 1 gp120 to CXCR4 induces mitochondrial transmembrane depolarization and cytochrome c-mediated apoptosis independently of Fas signaling.Making sense of how HIV kills infected CD4 T cells: implications for HIV cure.
P2860
Primary HIV-1 infection of human CD4+ T cells passaged into SCID mice leads to selection of chronically infected cells through a massive fas-mediated autocrine suicide of uninfected cells.
description
2000 nî lūn-bûn
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2000年の論文
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2000年論文
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name
Primary HIV-1 infection of hum ...... e suicide of uninfected cells.
@en
Primary HIV-1 infection of hum ...... e suicide of uninfected cells.
@nl
type
label
Primary HIV-1 infection of hum ...... e suicide of uninfected cells.
@en
Primary HIV-1 infection of hum ...... e suicide of uninfected cells.
@nl
prefLabel
Primary HIV-1 infection of hum ...... e suicide of uninfected cells.
@en
Primary HIV-1 infection of hum ...... e suicide of uninfected cells.
@nl
P2093
P2860
P356
P1476
Primary HIV-1 infection of hum ...... e suicide of uninfected cells.
@en
P2093
Belardelli F
Proietti E
Santini SM
P2860
P2888
P356
10.1038/SJ.CDD.4400586
P577
2000-01-01T00:00:00Z
P5875
P6179
1026685298