Distinct molecular mechanisms of acquired resistance to temozolomide in glioblastoma cells.
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Inhibition of prolyl 4-hydroxylase, beta polypeptide (P4HB) attenuates temozolomide resistance in malignant glioma via the endoplasmic reticulum stress response (ERSR) pathwaysA New Epigenetic Mechanism of Temozolomide Action in Glioma CellsTemozolomide Resistance in Glioblastoma Cell Lines: Implication of MGMT, MMR, P-Glycoprotein and CD133 ExpressionMetabolic targeting of EGFRvIII/PDK1 axis in temozolomide resistant glioblastoma.Differential expression of miR200a-3p and miR21 in grade II-III and grade IV gliomas: evidence that miR200a-3p is regulated by O⁶-methylguanine methyltransferase and promotes temozolomide responsiveness.Quantification and expert evaluation of evidence for chemopredictive biomarkers to personalize cancer treatment.The medicinal chemistry of imidazotetrazine prodrugsModulation of A1 and A2B adenosine receptor activity: a new strategy to sensitise glioblastoma stem cells to chemotherapy.Glioma cell death induced by irradiation or alkylating agent chemotherapy is independent of the intrinsic ceramide pathway.Major differences between tumor and normal human cell fates after exposure to chemotherapeutic monofunctional alkylatorAKT2-knockdown suppressed viability with enhanced apoptosis, and attenuated chemoresistance to temozolomide of human glioblastoma cells in vitro and in vivo.Bone morphogenetic protein 7 sensitizes O6-methylguanine methyltransferase expressing-glioblastoma stem cells to clinically relevant dose of temozolomide.Impact of temozolomide on immune response during malignant glioma chemotherapyTumor Suppressor WWOX and p53 Alterations and Drug Resistance in Glioblastomas.Temozolomide promotes genomic and phenotypic changes in glioblastoma cells.Core pathway mutations induce de-differentiation of murine astrocytes into glioblastoma stem cells that are sensitive to radiation but resistant to temozolomide.Expression of dynein, cytoplasmic 2, heavy chain 1 (DHC2) associated with glioblastoma cell resistance to temozolomide.Refined brain tumor diagnostics and stratified therapies: the requirement for a multidisciplinary approach.Molecular targets in glioblastoma.Temozolomide resistance in glioblastoma cells occurs partly through epidermal growth factor receptor-mediated induction of connexin 43.Re-irradiation after gross total resection of recurrent glioblastoma : Spatial pattern of recurrence and a review of the literature as a basis for target volume definition.Temozolomide induces the expression of the glioma Big Potassium (gBK) ion channel, while inhibiting fascin-1 expression: possible targets for glioma therapy.Augmented HR Repair Mediates Acquired Temozolomide Resistance in Glioblastoma.Topological robustness analysis of protein interaction networks reveals key targets for overcoming chemotherapy resistance in glioma.Valproic acid sensitizes human glioma cells to gefitinib-induced autophagy.Biological activity of tumor-treating fields in preclinical glioma models.c-Myc-miR-29c-REV3L signalling pathway drives the acquisition of temozolomide resistance in glioblastoma.Is more better? The impact of extended adjuvant temozolomide in newly diagnosed glioblastoma: a secondary analysis of EORTC and NRG Oncology/RTOG.Immunological effects of chemotherapy and radiotherapy against brain tumors.DNA methylation pyrosequencing assay is applicable for the assessment of epigenetic active environmental or clinical relevant chemicals.Therapeutic strategies of drug repositioning targeting autophagy to induce cancer cell death: from pathophysiology to treatment.MicroRNA-138 promotes acquired alkylator resistance in glioblastoma by targeting the Bcl-2-interacting mediator BIM.Chemoprotection in brain tumor patients: another success for stem cell gene therapy.Clinical and economic evaluation of modulated electrohyperthermia concurrent to dose-dense temozolomide 21/28 days regimen in the treatment of recurrent glioblastoma: a retrospective analysis of a two-centre German cohort trial with systematic compaAscochlorin Suppresses MMP-2-Mediated Migration and Invasion by Targeting FAK and JAK-STAT Signaling Cascades.FBW7 is associated with prognosis, inhibits malignancies and enhances temozolomide sensitivity in glioblastoma cells.Alterations in Cell Motility, Proliferation, and Metabolism in Novel Models of Acquired Temozolomide Resistant Glioblastoma.miR-519a enhances chemosensitivity and promotes autophagy in glioblastoma by targeting STAT3/Bcl2 signaling pathway.
P2860
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P2860
Distinct molecular mechanisms of acquired resistance to temozolomide in glioblastoma cells.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Distinct molecular mechanisms ...... olomide in glioblastoma cells.
@en
Distinct molecular mechanisms ...... olomide in glioblastoma cells.
@nl
type
label
Distinct molecular mechanisms ...... olomide in glioblastoma cells.
@en
Distinct molecular mechanisms ...... olomide in glioblastoma cells.
@nl
prefLabel
Distinct molecular mechanisms ...... olomide in glioblastoma cells.
@en
Distinct molecular mechanisms ...... olomide in glioblastoma cells.
@nl
P2093
P50
P1476
Distinct molecular mechanisms ...... olomide in glioblastoma cells.
@en
P2093
Ana-Maria Florea
Caroline Happold
Manuela Silginer
Natalie Schmidt
Patrick Roth
P304
P356
10.1111/J.1471-4159.2012.07781.X
P407
P577
2012-05-28T00:00:00Z