Proteasome inhibitor interacts synergistically with autophagy inhibitor to suppress proliferation and induce apoptosis in hepatocellular carcinoma. - Wikidata - wikimedia - TriplyDB

Proteasome inhibitor interacts synergistically with autophagy inhibitor to suppress proliferation and induce apoptosis in hepatocellular carcinoma.

Proteasome inhibitor interacts synergistically with autophagy inhibitor to suppress proliferation and induce apoptosis in hepatocellular carcinoma.

http://www.wikidata.org/entity/Q39361933

about

Autophagy in hepatocellular carcinomas: from pathophysiology to therapeutic response Autophagy in thyroid cancer: present knowledge and future perspectives C/EBPβ regulates sensitivity to bortezomib in prostate cancer cells by inducing REDD1 and autophagosome-lysosome fusion Autophagy and cancer therapy.Proteasome inhibitor MG132 inhibits the proliferation and promotes the cisplatin-induced apoptosis of human esophageal squamous cell carcinoma cells.JNK pathway mediates curcumin-induced apoptosis and autophagy in osteosarcoma MG63 cells.The ubiquitin-proteasome system: opportunities for therapeutic intervention in solid tumors Phase II trial of bortezomib plus doxorubicin in hepatocellular carcinoma (E6202): a trial of the Eastern Cooperative Oncology Group Combined autophagy and proteasome inhibition: a phase 1 trial of hydroxychloroquine and bortezomib in patients with relapsed/refractory myeloma.Coordinate autophagy and mTOR pathway inhibition enhances cell death in melanoma.Bortezomib enhances cancer cell death by blocking the autophagic flux through stimulating ERK phosphorylation.JNK and macroautophagy activation by bortezomib has a pro-survival effect in primary effusion lymphoma cells.Chloroquine inhibits hepatocellular carcinoma cell growth in vitro and in vivo.Broad targeting of resistance to apoptosis in cancer.Bortezomib effect on E2F and cyclin family members in human hepatocellular carcinoma cell lines.Autophagy: A novel therapeutic target for hepatocarcinoma (Review).Modulation of autophagy for the treatment of liver diseases.Autophagy and cancer metabolism.Untangling knots between autophagic targets and candidate drugs, in cancer therapy.The Proteasome Inhibitor Bortezomib Maintains Osteocyte Viability in Multiple Myeloma Patients by Reducing Both Apoptosis and Autophagy: A New Function for Proteasome Inhibitors.Mechanisms of resistance to apoptosis in the human acute promyelocytic leukemia cell line NB4.Bortezomib Treatment Sensitizes Oncolytic HSV-1-Treated Tumors to NK Cell Immunotherapy.Repurposing Drugs in Oncology (ReDO)-chloroquine and hydroxychloroquine as anti-cancer agents.Perturbation of proteasome function by bortezomib leading to ER stress-induced apoptotic cell death in cholangiocarcinoma.Preclinical evaluation of antitumor activity of the proteasome inhibitor MLN2238 (ixazomib) in hepatocellular carcinoma cells.Trehalose Inhibits Protein Aggregation Caused by Transient Ischemic Insults Through Preservation of Proteasome Activity, Not via Induction of Autophagy.Complex role of NK cells in regulation of oncolytic virus-bortezomib therapy.Ubiquitin-specific protease 7 accelerates p14(ARF) degradation by deubiquitinating thyroid hormone receptor-interacting protein 12 and promotes hepatocellular carcinoma progression.Ubiquitin Receptor RPN13 Mediates the Inhibitory Interaction of Diphenyldihaloketones CLEFMA and EF24 With the 26S Proteasome

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P2860

Proteasome inhibitor interacts synergistically with autophagy inhibitor to suppress proliferation and induce apoptosis in hepatocellular carcinoma.

http://www.wikidata.org/entity/Q39361933

description

2012 nî lūn-bûn

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2012年の論文

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年學術文章

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2012年學術文章

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2012年學術文章

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name

Proteasome inhibitor interacts ...... s in hepatocellular carcinoma.

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Proteasome inhibitor interacts ...... s in hepatocellular carcinoma.

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type

label

Proteasome inhibitor interacts ...... s in hepatocellular carcinoma.

@en

Proteasome inhibitor interacts ...... s in hepatocellular carcinoma.

@nl

prefLabel

Proteasome inhibitor interacts ...... s in hepatocellular carcinoma.

@en

Proteasome inhibitor interacts ...... s in hepatocellular carcinoma.

@nl

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Proteasome inhibitor interacts ...... s in hepatocellular carcinoma.

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P2093

Bo Hui

http://www.w3.org/2001/XMLSchema#string

Cheng-Yu Gu

http://www.w3.org/2001/XMLSchema#string

Guo-Ming Shi

http://www.w3.org/2001/XMLSchema#string

Hua Yang

http://www.w3.org/2001/XMLSchema#string

Jia Fan

http://www.w3.org/2001/XMLSchema#string

Jian Zhou

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Wei-Ren Liu

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Ying-Hong Shi

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Yuan-Fei Peng

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Zhen-Bin Ding

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P2860

Death and anti-death: tumour resistance to apoptosis

Hepatocellular carcinoma: epidemiology and molecular carcinogenesis

A role for ubiquitin in selective autophagy

Autophagy in cell death: an innocent convict?

Identification of overexpressed genes in hepatocellular carcinoma, with special reference to ubiquitin-conjugating enzyme E2C gene expression.

Targeted proteasome inhibition by Velcade induces apoptosis in human mesothelioma and breast cancer cell lines.

The role of Myc-induced protein synthesis in cancer.

Endoplasmic reticulum stress triggers autophagy.

Autophagy: molecular mechanisms, physiological functions and relevance in human pathology.

Proteasome inhibition and its clinical prospects in the treatment of hematologic and solid malignancies.

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5560-5571

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10.1002/CNCR.27586

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22

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22517429

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apoptotic process