Xenobiotic metabolism capacities of human skin in comparison with a 3D epidermis model and keratinocyte-based cell culture as in vitro alternatives for chemical testing: activating enzymes (Phase I).
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Xenobiotic-metabolizing enzymes in the skin of rat, mouse, pig, guinea pig, man, and in human skin modelsPredicting full thickness skin sensitization using a support vector machineElucidation of xenobiotic metabolism pathways in human skin and human skin models by proteomic profiling3D In vitro model of a functional epidermal permeability barrier from human embryonic stem cells and induced pluripotent stem cells.The expanding world of tissue engineering: the building blocks and new applications of tissue engineered constructs.Emerging in vitro models for safety screening of high-volume production nanomaterials under environmentally relevant exposure conditions.Functions of the aryl hydrocarbon receptor in the skin.Activation of non-sensitizing or low-sensitizing fragrance substances into potent sensitizers - prehaptens and prohaptens.Bioactivation of drugs in the skin: relationship to cutaneous adverse drug reactions.Extrahepatic metabolism at the body's internal-external interfaces.Perspectives on percutaneous penetration: Silica nanoparticles.Metabolic and redox barriers in the skin exposed to drugs and xenobiotics.Development of a Full-Thickness Human Skin Equivalent In Vitro Model Derived from TERT-Immortalized Keratinocytes and Fibroblasts.Extracellular signal-regulated kinases 1/2 and Akt contribute to triclosan-stimulated proliferation of JB6 Cl 41-5a cells.Xenobiotic metabolizing enzyme activities in cells used for testing skin sensitization in vitro.Use of human in vitro skin models for accurate and ethical risk assessment: metabolic considerations.Effect of Repeated Daily Dosing with 2,4-Dinitrochlorobenzene on Glutathione Biosynthesis and Nrf2 Activation in Reconstructed Human Epidermis.Stilbenes and resveratrol metabolites improve mitochondrial fatty acid oxidation defects in human fibroblasts.Induction of a chloracne phenotype in an epidermal equivalent model by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) is dependent on aryl hydrocarbon receptor activation and is not reproduced by aryl hydrocarbon receptor knock down.The Metabolism of Methazolamide in Immortalized Human Keratinocytes, HaCaT Cells.Filling the gaps: need for research on cell-specific xenobiotic metabolism in the skin.The next three decades of the comet assay: a report of the 11th International Comet Assay Workshop.Biotransformation of 2,4-toluenediamine in human skin and reconstructed tissues.Human skin gene expression: Natural (trans) resveratrol versus five resveratrol analogs for dermal applications.Morphine metabolism in human skin microsomes.Skin response to a carcinogen involves the xenobiotic receptor pregnane X receptor.Comparison of xenobiotic metabolizing enzyme activities in ex vivo human skin and reconstructed human skin models from SkinEthic.Xenobiotica-metabolizing enzymes in the skin of rat, mouse, pig, guinea pig, man, and in human skin models
P2860
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P2860
Xenobiotic metabolism capacities of human skin in comparison with a 3D epidermis model and keratinocyte-based cell culture as in vitro alternatives for chemical testing: activating enzymes (Phase I).
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
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2012年學術文章
@zh-hant
name
Xenobiotic metabolism capaciti ...... activating enzymes (Phase I).
@en
Xenobiotic metabolism capaciti ...... al testing: activating enzymes
@nl
type
label
Xenobiotic metabolism capaciti ...... activating enzymes (Phase I).
@en
Xenobiotic metabolism capaciti ...... al testing: activating enzymes
@nl
prefLabel
Xenobiotic metabolism capaciti ...... activating enzymes (Phase I).
@en
Xenobiotic metabolism capaciti ...... al testing: activating enzymes
@nl
P2093
P2860
P1476
Xenobiotic metabolism capaciti ...... : activating enzymes (Phase I)
@en
P2093
Camilla Pease
Carsten Goebel
Christine Götz
Christine Jäckh
Ellen Fritsche
Eric Fabian
Eva-Maria Freytag
Hans F Merk
Jean Krutmann
Nicola Hewitt
P2860
P304
P356
10.1111/J.1600-0625.2012.01486.X
P50
P577
2012-05-01T00:00:00Z