Prenatal human ocular degeneration occurs in Leber's congenital amaurosis (LCA2).
about
Recombinant adeno-associated virus type 2-mediated gene delivery into the Rpe65-/- knockout mouse eye results in limited rescueSynaptogenesis and outer segment formation are perturbed in the neural retina of Crx mutant miceIdentifying photoreceptors in blind eyes caused by RPE65 mutations: Prerequisite for human gene therapy success.Leber congenital amaurosis due to RPE65 mutations and its treatment with gene therapyThe retinal pigment epithelium in health and diseaseMutation of key residues of RPE65 abolishes its enzymatic role as isomerohydrolase in the visual cycle.Delivery of adeno-associated virus vectors to the fetal retina: impact of viral capsid proteins on retinal neuronal progenitor transductionHistopathology and functional correlations in a patient with a mutation in RPE65, the gene for retinol isomerase.The frequency-response electroretinogram distinguishes cone and abnormal rod function in rd12 mice.Leber congenital amaurosis: a genetic paradigm.Human retinal gene therapy for Leber congenital amaurosis shows advancing retinal degeneration despite enduring visual improvementHuman gene therapy for RPE65 isomerase deficiency activates the retinoid cycle of vision but with slow rod kinetics.Defining the residual vision in leber congenital amaurosis caused by RPE65 mutations.Gene therapy for Leber congenital amaurosis: advances and future directions.Photoreceptor layer topography in children with leber congenital amaurosis caused by RPE65 mutations.Concepts and Strategies in Retinal Gene Therapy.Abnormal retinal architecture in a 33-week-old fetus with LCA and a homozygous C330Y mutation in RPE65.Safety and Long-Term Efficacy of AAV4 Gene Therapy in Patients with RPE65 Leber Congenital Amaurosis.Histopathologic-genotypic correlations in retinitis pigmentosa and allied diseases.
P2860
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P2860
Prenatal human ocular degeneration occurs in Leber's congenital amaurosis (LCA2).
description
2002 nî lūn-bûn
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2002年の論文
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2002年学术文章
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2002年学术文章
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2002年学术文章
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2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
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2002年學術文章
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2002年學術文章
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name
Prenatal human ocular degeneration occurs in Leber's congenital amaurosis (LCA2).
@en
Prenatal human ocular degeneration occurs in Leber's congenital amaurosis
@nl
type
label
Prenatal human ocular degeneration occurs in Leber's congenital amaurosis (LCA2).
@en
Prenatal human ocular degeneration occurs in Leber's congenital amaurosis
@nl
prefLabel
Prenatal human ocular degeneration occurs in Leber's congenital amaurosis (LCA2).
@en
Prenatal human ocular degeneration occurs in Leber's congenital amaurosis
@nl
P2093
P50
P356
P1476
Prenatal human ocular degeneration occurs in Leber's congenital amaurosis (LCA2).
@en
P2093
David Hicks
Fernanda B O Porto
Noëlle Hanoteau
Sylvain Hanein
P304
P356
10.1002/JGM.278
P577
2002-07-01T00:00:00Z