Dynamically regulated sumoylation of HDAC2 controls p53 deacetylation and restricts apoptosis following genotoxic stress.
about
Histone deacetylase 2 and N-Myc reduce p53 protein phosphorylation at serine 46 by repressing gene transcription of tumor protein 53-induced nuclear protein 1Functional characterization of novel mutations affecting survivin (BIRC5)-mediated therapy resistance in head and neck cancer patients.Small-molecular modulators of cancer-associated epigenetic mechanisms.SUMOylation occurs in acute kidney injury and plays a cytoprotective roleRole of histone deacetylase 2 and its posttranslational modifications in cardiac hypertrophy.Exposure to atheroma-relevant 7-oxysterols causes proteomic alterations in cell death, cellular longevity, and lipid metabolism in THP-1 macrophagesInvestigating the Sensitivity of NAD+-dependent Sirtuin Deacylation Activities to NADHp53-dependent and p53-independent anticancer effects of different histone deacetylase inhibitors.Anticancer effects of valproic acid on oral squamous cell carcinoma via SUMOylation in vivo and in vitro.Delaying histone deacetylase response to injury accelerates conversion into repair Schwann cells and nerve regeneration.STAT5 acetylation: Mechanisms and consequences for immunological control and leukemogenesis.Computational genomic analysis of PARK7 interactome reveals high BBS1 gene expression as a prognostic factor favoring survival in malignant pleural mesothelioma.Sumoylation of HDAC2 promotes NF-κB-dependent gene expression.Sub-cellular localization specific SUMOylation in the heart.HIV-1 Vpr reactivates latent HIV-1 provirus by inducing depletion of class I HDACs on chromatin.Acetylation and sumoylation control STAT5 activation antagonistically.Aberrant expression and activity of histone deacetylases in sporadic idiopathic pulmonary fibrosis.The Hydra small ubiquitin-like modifier.SIRT3 deregulation is linked to mitochondrial dysfunction in Alzheimer's disease.Analysis of Histone Deacetylases Sumoylation by Immunoprecipitation Techniques.TFIIA transcriptional activity is controlled by a 'cleave-and-run' Exportin-1/Taspase 1-switch.SUMOylation of HDAC2 with SUMO1Detection of Sumo Modification of Endogenous Histone Deacetylase 2 (HDAC2) in Mammalian Cells.Role of novel histone modifications in cancer.Quantitative phosphoproteomic analysis reveals γ-bisabolene inducing p53-mediated apoptosis of human oral squamous cell carcinoma via HDAC2 inhibition and ERK1/2 activation.Expressional analysis of disease-relevant signalling-pathways in primary tumours and metastasis of head and neck cancers.Establishment, functional and genetic characterization of a colon derived large cell neuroendocrine carcinoma cell lineTricho-rhino-phalangeal syndrome 1 protein functions as a scaffold required for ubiquitin-specific protease 4-directed histone deacetylase 2 de-ubiquitination and tumor growth
P2860
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P2860
Dynamically regulated sumoylation of HDAC2 controls p53 deacetylation and restricts apoptosis following genotoxic stress.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
Dynamically regulated sumoylat ...... is following genotoxic stress.
@en
Dynamically regulated sumoylat ...... is following genotoxic stress.
@nl
type
label
Dynamically regulated sumoylat ...... is following genotoxic stress.
@en
Dynamically regulated sumoylat ...... is following genotoxic stress.
@nl
prefLabel
Dynamically regulated sumoylat ...... is following genotoxic stress.
@en
Dynamically regulated sumoylat ...... is following genotoxic stress.
@nl
P2093
P2860
P50
P356
P1476
Dynamically regulated sumoylat ...... is following genotoxic stress.
@en
P2093
André Brandl
Günter Schneider
Katharina M Uhlig
Thorsten Heinzel
Tobias Wagner
P2860
P304
P356
10.1093/JMCB/MJS013
P577
2012-04-05T00:00:00Z