Genetic disruption of Pten in a novel mouse model of tomaculous neuropathy. - Wikidata - wikimedia - TriplyDB

Genetic disruption of Pten in a novel mouse model of tomaculous neuropathy.

Genetic disruption of Pten in a novel mouse model of tomaculous neuropathy.

http://www.wikidata.org/entity/Q39367129

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Balancing Proliferation and Connectivity in PTEN-associated Autism Spectrum Disorder New insights on Schwann cell development MicroRNA-23a promotes myelination in the central nervous system Motor and sensory neuropathy due to myelin infolding and paranodal damage in a transgenic mouse model of Charcot-Marie-Tooth disease type 1C.Lck tyrosine kinase mediates β1-integrin signalling to regulate Schwann cell migration and myelination Metabolic regulator LKB1 is crucial for Schwann cell-mediated axon maintenance.Pten loss in Olig2 expressing neural progenitor cells and oligodendrocytes leads to interneuron dysplasia and leukodystrophy.Abnormal junctions and permeability of myelin in PMP22-deficient nerves.Late onset neuropathy with spontaneous clinical remission in mice lacking the POZ domain of the transcription factor Myc-interacting zinc finger protein 1 (Miz1) in Schwann cells Involvement of phosphatase and tensin homolog deleted from chromosome 10 in rodent model of neuropathic pain.Regulation of Peripheral Nerve Myelin Maintenance by Gene Repression through Polycomb Repressive Complex 2 The Polarity Protein Pals1 Regulates Radial Sorting of Axons Hypomyelination following deletion of Tsc2 in oligodendrocyte precursors.Myelin is dependent on the Charcot-Marie-Tooth Type 4H disease culprit protein FRABIN/FGD4 in Schwann cells The CMT4B disease-causing phosphatases Mtmr2 and Mtmr13 localize to the Schwann cell cytoplasm and endomembrane compartments, where they depend upon each other to achieve wild-type levels of protein expression.Reversing hypomyelination in BACE1-null mice with Akt-DD overexpression.Neurological dysfunctions associated with altered BACE1-dependent Neuregulin-1 signaling.Akt Regulates Axon Wrapping and Myelin Sheath Thickness in the PNS Genetic deletion of Cadm4 results in myelin abnormalities resembling Charcot-Marie-Tooth neuropathy.Strength of ERK1/2 MAPK Activation Determines Its Effect on Myelin and Axonal Integrity in the Adult CNS.Schwann Cell O-GlcNAc Glycosylation Is Required for Myelin Maintenance and Axon Integrity.Niacin-mediated Tace activation ameliorates CMT neuropathies with focal hypermyelination.DDIT4/REDD1/RTP801 is a novel negative regulator of Schwann cell myelination.Genetic heterogeneity of motor neuropathies Negative regulators of schwann cell differentiation-novel targets for peripheral nerve therapies?Signaling mechanisms regulating myelination in the central nervous system.Akt/mTOR signalling in myelination.Concepts for regulation of axon integrity by enwrapping glia.Brain patterning perturbations following PTEN loss.Neuregulin-ERBB signaling in the nervous system and neuropsychiatric diseases Schwann cell myelination Dysregulation of ErbB Receptor Trafficking and Signaling in Demyelinating Charcot-Marie-Tooth Disease.mTORC1 promotes proliferation of immature Schwann cells and myelin growth of differentiated Schwann cells.Molecular Mechanisms Involved in Schwann Cell Plasticity Schwann cell development, maturation and regeneration: a focus on classic and emerging intracellular signaling pathways Dual function of the PI3K-Akt-mTORC1 axis in myelination of the peripheral nervous system.Activation of MAPK overrides the termination of myelin growth and replaces Nrg1/ErbB3 signals during Schwann cell development and myelination.Merlin controls the repair capacity of Schwann cells after injury by regulating Hippo/YAP activity.Giant scaffolding protein AHNAK1 interacts with β-dystroglycan and controls motility and mechanical properties of Schwann cells.Therapeutic implications of protein homeostasis in demyelinating peripheral neuropathies.

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P2860

Genetic disruption of Pten in a novel mouse model of tomaculous neuropathy.

http://www.wikidata.org/entity/Q39367129

description

2012 nî lūn-bûn

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2012年の論文

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年学术文章

@zh-my

2012年学术文章

@zh-sg

2012年學術文章

@yue

2012年學術文章

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2012年學術文章

@zh-hant

name

Genetic disruption of Pten in a novel mouse model of tomaculous neuropathy.

@en

Genetic disruption of Pten in a novel mouse model of tomaculous neuropathy.

@nl

type

label

Genetic disruption of Pten in a novel mouse model of tomaculous neuropathy.

@en

Genetic disruption of Pten in a novel mouse model of tomaculous neuropathy.

@nl

prefLabel

Genetic disruption of Pten in a novel mouse model of tomaculous neuropathy.

@en

Genetic disruption of Pten in a novel mouse model of tomaculous neuropathy.

@nl

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EMBO Molecular Medicine

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Genetic disruption of Pten in a novel mouse model of tomaculous neuropathy.

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Alexander Pieper

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Georg L Wieser

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Jan H Oltrogge

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Michael W Sereda

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Sandra Goebbels

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Susanne Wolfer

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Tobias Nientiedt

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Torben Ruhwedel

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P2860

Threonine phosphorylation of the MMAC1/PTEN PDZ binding domain both inhibits and stimulates PDZ binding

Evidence for regulation of the PTEN tumor suppressor by a membrane-localized multi-PDZ domain containing scaffold protein MAGI-2

Protean PTEN: form and function

Distinct claudins and associated PDZ proteins form different autotypic tight junctions in myelinating Schwann cells

Peripheral nerve demyelination caused by a mutant Rho GTPase guanine nucleotide exchange factor, frabin/FGD4

Mutations in FGD4 encoding the Rho GDP/GTP exchange factor FRABIN cause autosomal recessive Charcot-Marie-Tooth type 4H

Tamoxifen-inducible glia-specific Cre mice for somatic mutagenesis in oligodendrocytes and Schwann cells

Regulation of an activated S6 kinase 1 variant reveals a novel mammalian target of rapamycin phosphorylation site

Mutations in the pleckstrin homology domain of dynamin 2 cause dominant intermediate Charcot-Marie-Tooth disease

Axonal neuregulin-1 regulates myelin sheath thickness

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10.1002/EMMM.201200227

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6

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