ErbB2-driven breast cancer cell invasion depends on a complex signaling network activating myeloid zinc finger-1-dependent cathepsin B expression.
about
Group II p21-activated kinases as therapeutic targets in gastrointestinal cancerPAK4 promotes kinase-independent stabilization of RhoU to modulate cell adhesionBuilding bridges toward invasion: tumor promoter treatment induces a novel protein kinase C-dependent phenotype in MCF10A mammary cell aciniTOM1L1 drives membrane delivery of MT1-MMP to promote ERBB2-induced breast cancer cell invasion.Cell type-dependent pathogenic functions of overexpressed human cathepsin B in murine breast cancer progressionIdentification of cytoskeleton-associated proteins essential for lysosomal stability and survival of human cancer cellsThe Mutational Landscape of the Oncogenic MZF1 SCAN Domain in Cancer.S100A11 is required for efficient plasma membrane repair and survival of invasive cancer cells.Vascular Endothelial Growth Factor (VEGF) Promotes Assembly of the p130Cas Interactome to Drive Endothelial Chemotactic Signaling and Angiogenesis.Pericellular proteolysis in cancerA kinase inhibitor screen reveals protein kinase C-dependent endocytic recycling of ErbB2 in breast cancer cells.Genomic insights into triple-negative and HER2-positive breast cancers using isogenic model systemsLysosomal protein turnover contributes to the acquisition of TGFβ-1 induced invasive properties of mammary cancer cells.Overexpression of EMMPRIN isoform 2 is associated with head and neck cancer metastasisS100 and annexin proteins identify cell membrane damage as the Achilles heel of metastatic cancer cells.A novel small-molecule MRCK inhibitor blocks cancer cell invasionProton irradiation augments the suppression of tumor progression observed with advanced age.Heregulin-HER3-HER2 signaling promotes matrix metalloproteinase-dependent blood-brain-barrier transendothelial migration of human breast cancer cell lines.The transcription factors Ik-1 and MZF1 downregulate IGF-IR expression in NPM-ALK⁺ T-cell lymphomaOsteopontin mediates an MZF1-TGF-β1-dependent transformation of mesenchymal stem cells into cancer-associated fibroblasts in breast cancerStress-resistant Translation of Cathepsin L mRNA in Breast Cancer ProgressionTargeting Cathepsin B for Cancer Therapies.Cell-matrix interactions: focus on proteoglycan-proteinase interplay and pharmacological targeting in cancer.Effect of low doses of estradiol and tamoxifen on breast cancer cell karyotypesThe actin-myosin regulatory MRCK kinases: regulation, biological functions and associations with human cancer.A novel orally bioavailable compound KPT-9274 inhibits PAK4, and blocks triple negative breast cancer tumor growth.Cancer-associated lysosomal changes: friends or foes?Role and Regulation of Myeloid Zinc Finger Protein 1 in Cancer.When Good Turns Bad: Regulation of Invasion and Metastasis by ErbB2 Receptor Tyrosine Kinase.High level PHGDH expression in breast is predominantly associated with keratin 5-positive cell lineage independently of malignancy.Myeloid zinc-finger 1 (MZF-1) suppresses prostate tumor growth through enforcing ferroportin-conducted iron egress.Cathepsin B-deficient mice as source of monoclonal anti-cathepsin B antibodiesCIP2A oncoprotein controls cell growth and autophagy through mTORC1 activation.The Pak4 protein kinase is required for oncogenic transformation of MDA-MB-231 breast cancer cells.Screening and identification of small molecule inhibitors of ErbB2-induced invasion.The pak4 protein kinase in breast cancer.A way to invade: a story of ErbB2 and lysosomes.C1q-tumour necrosis factor-related protein 8 (CTRP8) is a novel interaction partner of relaxin receptor RXFP1 in human brain cancer cells.Ragulator-a multifaceted regulator of lysosomal signaling and trafficking.Let-7 microRNA controls invasion-promoting lysosomal changes via the oncogenic transcription factor myeloid zinc finger-1.
P2860
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P2860
ErbB2-driven breast cancer cell invasion depends on a complex signaling network activating myeloid zinc finger-1-dependent cathepsin B expression.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
ErbB2-driven breast cancer cel ...... endent cathepsin B expression.
@en
ErbB2-driven breast cancer cel ...... endent cathepsin B expression.
@nl
type
label
ErbB2-driven breast cancer cel ...... endent cathepsin B expression.
@en
ErbB2-driven breast cancer cel ...... endent cathepsin B expression.
@nl
prefLabel
ErbB2-driven breast cancer cel ...... endent cathepsin B expression.
@en
ErbB2-driven breast cancer cel ...... endent cathepsin B expression.
@nl
P2093
P50
P1433
P1476
ErbB2-driven breast cancer cel ...... pendent cathepsin B expression
@en
P2093
Charlotta Johanne Olsen
Christina Egebjerg
Elisabeth Corcelle-Termeau
Nicole Fehrenbacher
Piotr Szyniarowski
Sofie Hagel Andersen
Trine Bøttzauw
Tuula Kallunki
P304
P356
10.1016/J.MOLCEL.2012.01.029
P50
P577
2012-03-01T00:00:00Z