Triple bioorthogonal ligation strategy for simultaneous labeling of multiple enzymatic activities.
about
Bioorthogonal chemistry: strategies and recent developmentsDecreasing Distortion Energies without Strain: Diazo-Selective 1,3-Dipolar CycloadditionsBioconjugation of therapeutic proteins and enzymes using the expanded set of genetically encoded amino acids.Selective fluorescence detection of small-molecule-binding proteins by using a dual photoaffinity labeling system.Discovery of new mutually orthogonal bioorthogonal cycloaddition pairs through computational screeningSimultaneous Site-Specific Dual Protein Labeling Using Protein Prenyltransferases.Activity-based imaging probes of the proteasome.Synthesis of post-translationally modified proteins.Sum of the parts: mass spectrometry-based metabolomicsInverse electron demand Diels-Alder (iEDDA)-initiated conjugation: a (high) potential click chemistry scheme.Activity-based protein profiling: recent advances in probe development and applications.Affinity purification in target identification: the specificity challenge.Metabolic Glycoengineering with N-Acyl Side Chain Modified Mannosamines.A cascading reaction sequence involving ligand-directed azaelectrocyclization and autooxidation-induced fluorescence recovery enables visualization of target proteins on the surfaces of live cells.Activity-based probes for the multicatalytic proteasome.Detection of bioorthogonal groups by correlative light and electron microscopy allows imaging of degraded bacteria in phagocytes.Fine-Tuning Strain and Electronic Activation of Strain-Promoted 1,3-Dipolar Cycloadditions with Endocyclic Sulfamates in SNO-OCTsProtein modification via alkyne hydrosilylation using a substoichiometric amount of ruthenium(ii) catalyst.Expanding the scope of cyclopropene reporters for the detection of metabolically engineered glycoproteins by Diels-Alder reactions.Bioorthogonal chemistry for (68) Ga radiolabelling of DOTA-containing compounds.Relative quantification of proteasome activity by activity-based protein profiling and LC-MS/MS.Development of bis-unsaturated ester aldehydes as amino-glue probes: sequential double azaelectrocyclization as a promising strategy for bioconjugation.Direct Synthesis of β-Aminoenals through Reaction of 1,2,3-Triazine with Secondary Amines.A Suite of "Minimalist" Photo-Crosslinkers for Live-Cell Imaging and Chemical Proteomics: Case Study with BRD4 Inhibitors.Vinylboronic Acids as Efficient Bioorthogonal Reactants for Tetrazine Labeling in Living Cells.Novel activity-based probes for N-acylethanolamine acid amidase.Photoaffinity labeling of small-molecule-binding proteins by DNA-templated chemistry.A multi-ligation strategy for the synthesis of heterofunctionalized glycosylated scaffolds.Exploring the Potential of Norbornene-Modified Mannosamine Derivatives for Metabolic Glycoengineering.A tetrazine templated method for the synthesis of ternary conjugates.Direct and two-step bioorthogonal probes for Bruton's tyrosine kinase based on ibrutinib: a comparative study.Copper-assisted click reactions for activity-based proteomics: fine-tuned ligands and refined conditions extend the scope of application.
P2860
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P2860
Triple bioorthogonal ligation strategy for simultaneous labeling of multiple enzymatic activities.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
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2012年學術文章
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name
Triple bioorthogonal ligation ...... multiple enzymatic activities.
@en
Triple bioorthogonal ligation ...... multiple enzymatic activities.
@nl
type
label
Triple bioorthogonal ligation ...... multiple enzymatic activities.
@en
Triple bioorthogonal ligation ...... multiple enzymatic activities.
@nl
prefLabel
Triple bioorthogonal ligation ...... multiple enzymatic activities.
@en
Triple bioorthogonal ligation ...... multiple enzymatic activities.
@nl
P2093
P2860
P356
P1476
Triple bioorthogonal ligation ...... multiple enzymatic activities.
@en
P2093
Bogdan I Florea
Gijsbert A van der Marel
Mark Ruben
P2860
P304
P356
10.1002/ANIE.201200923
P407
P577
2012-03-21T00:00:00Z