Pleiotropic phenotype of colchicine-resistant CHO cells: cross-resistance and collateral sensitivity.
about
Small and Innovative Molecules as New Strategy to Revert MDREffect of P-glycoprotein on flavopiridol sensitivityTargeting the Achilles heel of multidrug-resistant cancer by exploiting the fitness cost of resistance.Multidrug-resistance gene (P-glycoprotein) is expressed by endothelial cells at blood-brain barrier sites.Uptake of compounds that selectively kill multidrug-resistant cells: the copper transporter SLC31A1 (CTR1) increases cellular accumulation of the thiosemicarbazone NSC73306Generation of a drug resistance profile by quantitation of mdr-1/P-glycoprotein in the cell lines of the National Cancer Institute Anticancer Drug Screen.Expression of a full-length cDNA for the human "MDR1" gene confers resistance to colchicine, doxorubicin, and vinblastineThe multixenobiotic resistance mechanism in aquatic organisms.Hoechst 33342 dye uptake as a probe of membrane permeability changes in mammalian cells.Collateral sensitivity as a strategy against cancer multidrug resistance.Interaction of multidrug-resistant Chinese hamster ovary cells with amphiphilesInvestigation of the relationship between altered intracellular pH and multidrug resistance in mammalian cells.P388 leukaemia cells resistant to the anthracycline menogaril lack multidrug resistant phenotype.Reversal of intrinsic multidrug resistance in Chinese hamster ovary cells by amiloride analogsSelective growth-inhibition of multidrug-resistant CHO-cells by the monoclonal antibody 265/F4.Derivation and preliminary characterisation of adriamycin resistant lines of human lung cancer cells.Functional replacement of the hemolysin A transport signal by a different primary sequence.In situ biochemical demonstration that P-glycoprotein is a drug efflux pump with broad specificity.The molecular basis of multidrug resistance in cancer: the early years of P-glycoprotein research.Glutathione and related enzyme activity in human lung cancer cell lines.Overcoming multidrug resistance in Chinese hamster ovary cells in vitro by cyclosporin A (Sandimmune) and non-immunosuppressive derivatives.Multidrug resistance (mdr) genes in human cancer.MDR1 synonymous polymorphisms alter transporter specificity and protein stability in a stable epithelial monolayer.Expression of hamster P-glycoprotein and multidrug resistance in DNA-mediated transformants of mouse LTA cells.Functional intracellular P-glycoprotein.Co-amplification of double minute chromosomes, multiple drug resistance, and cell surface P-glycoprotein in DNA-mediated transformants of mouse cells.DNA-mediated transfer of multiple drug resistance and plasma membrane glycoprotein expression.P-glycoprotein efflux transporter activity often displays biphasic dose-response relationships.Is resistance useless? Multidrug resistance and collateral sensitivity.The clinical relevance of multidrug resistance.Inhibition of the multidrug resistance P-glycoprotein: time for a change of strategy?Multiply drug-resistant human KB carcinoma cells have decreased amounts of a 75-kDa and a 72-kDa glycoprotein.Cytogenetic and molecular characterization of random chromosomal rearrangements activating the drug resistance gene, MDR1/P-glycoprotein, in drug-selected cell lines and patients with drug refractory ALL.Transfected MDCK cell line with enhanced expression of CYP3A4 and P-glycoprotein as a model to study their role in drug transport and metabolism.Mechanisms of multidrug resistance and implications for therapy.Identification of a novel calcium-binding protein (CP22) in multidrug-resistant murine and hamster cells.Purification and characterization of NF-R2 that regulates the expression of the human multidrug resistance (MDR1) gene.Prediction of the clinical chemotherapeutic response of stage III lung adenocarcinoma patients by an in vitro short term test.Resistance to the antimitotic drug estramustine is distinct from the multidrug resistant phenotype.Constitutive expression of multidrug resistance in human colorectal tumours and cell lines.
P2860
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P2860
Pleiotropic phenotype of colchicine-resistant CHO cells: cross-resistance and collateral sensitivity.
description
1976 nî lūn-bûn
@nan
1976年の論文
@ja
1976年学术文章
@wuu
1976年学术文章
@zh-cn
1976年学术文章
@zh-hans
1976年学术文章
@zh-my
1976年学术文章
@zh-sg
1976年學術文章
@yue
1976年學術文章
@zh
1976年學術文章
@zh-hant
name
Pleiotropic phenotype of colch ...... ce and collateral sensitivity.
@en
Pleiotropic phenotype of colch ...... ce and collateral sensitivity.
@nl
type
label
Pleiotropic phenotype of colch ...... ce and collateral sensitivity.
@en
Pleiotropic phenotype of colch ...... ce and collateral sensitivity.
@nl
prefLabel
Pleiotropic phenotype of colch ...... ce and collateral sensitivity.
@en
Pleiotropic phenotype of colch ...... ce and collateral sensitivity.
@nl
P356
P1476
Pleiotropic phenotype of colch ...... ce and collateral sensitivity.
@en
P2093
Bech-Hansen NT
P2860
P356
10.1002/JCP.1040880104
P50
P577
1976-05-01T00:00:00Z