Targeting of 4-1BB by monoclonal antibody PF-05082566 enhances T-cell function and promotes anti-tumor activity.
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Natural Killer Cell Immunomodulation: Targeting Activating, Inhibitory, and Co-stimulatory Receptor Signaling for Cancer ImmunotherapyTrial Watch: Immunomodulatory monoclonal antibodies for oncological indicationsMilestones in the staging, classification, and biology of Merkel cell carcinomaAgonist antibodies to TNFR molecules that costimulate T and NK cellsTherapy of newly diagnosed follicular lymphoma.Clinical targeting of the TNF and TNFR superfamiliesHuman and mouse CD137 have predominantly different binding CRDs to their respective ligandsHumanized Mouse Models of Clinical Disease.Emerging and mechanism-based therapies for recurrent or metastatic Merkel cell carcinomaMultistep, effective drug distribution within solid tumors.Changes to International Nonproprietary Names for antibody therapeutics 2017 and beyond: of mice, men and more.Defining the optimal murine models to investigate immune checkpoint blockers and their combination with other immunotherapies.Harnessing co-stimulatory TNF receptors for cancer immunotherapy: Current approaches and future opportunities.Rationale for immune-based therapies in Merkel polyomavirus-positive and -negative Merkel cell carcinomas.Mouse models in oncoimmunology.PET imaging to non-invasively study immune activation leading to antitumor responses with a 4-1BB agonistic antibodyMerkel polyomavirus-specific T cells fluctuate with merkel cell carcinoma burden and express therapeutically targetable PD-1 and Tim-3 exhaustion markersFunctional optimization of agonistic antibodies to OX40 receptor with novel Fc mutations to promote antibody multimerization.Tumour necrosis factor receptor superfamily member 9 (TNFRSF9) is up-regulated in reactive astrocytes in human gliomas.PD-1 Blockade Prevents the Development and Progression of Carcinogen-Induced Oral Premalignant Lesions.Monoclonal Antibody Therapies for Hematological Malignancies: Not Just Lineage-Specific Targets.Unique pharmacology of a novel allosteric agonist/sensitizer insulin receptor monoclonal antibody.Productive common light chain libraries yield diverse panels of high affinity bispecific antibodies.Structure of the 4-1BB/4-1BBL complex and distinct binding and functional properties of utomilumab and urelumab
P2860
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P2860
Targeting of 4-1BB by monoclonal antibody PF-05082566 enhances T-cell function and promotes anti-tumor activity.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
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2012年學術文章
@zh-hant
name
Targeting of 4-1BB by monoclon ...... promotes anti-tumor activity.
@en
Targeting of 4-1BB by monoclon ...... promotes anti-tumor activity.
@nl
type
label
Targeting of 4-1BB by monoclon ...... promotes anti-tumor activity.
@en
Targeting of 4-1BB by monoclon ...... promotes anti-tumor activity.
@nl
prefLabel
Targeting of 4-1BB by monoclon ...... promotes anti-tumor activity.
@en
Targeting of 4-1BB by monoclon ...... promotes anti-tumor activity.
@nl
P2093
P2860
P1476
Targeting of 4-1BB by monoclon ...... promotes anti-tumor activity.
@en
P2093
Allison Rohner
Amy C Shen
Chunli Huang
Cris Kamperschroer
Leslie L Sharp
Paul D Lira
Regis Doyonnas
Sangita M Baxi
Sharon A Sokolowski
Simon Bergqvist
P2860
P2888
P304
P356
10.1007/S00262-012-1237-1
P577
2012-03-11T00:00:00Z