Histone demethylase KDM5B collaborates with TFAP2C and Myc to repress the cell cycle inhibitor p21(cip) (CDKN1A).
about
Histone demethylases in chromatin biology and beyondGenome-scale transcriptional activation by an engineered CRISPR-Cas9 complex.A chromatin activity-based chemoproteomic approach reveals a transcriptional repressome for gene-specific silencing.Processing Oscillatory Signals by Incoherent Feedforward Loops.HMGB1 promotes HCC progression partly by downregulating p21 via ERK/c-Myc pathway and upregulating MMP-2Overexpression of JARID1B promotes differentiation via SHIP1/AKT signaling in human hypopharyngeal squamous cell carcinoma.Original Research: miR-194 inhibits proliferation and invasion and promotes apoptosis by targeting KDM5B in esophageal squamous cell carcinoma cells.Histone H3K4 trimethylation: dynamic interplay with pre-mRNA splicing.TFAP2C promotes lung tumorigenesis and aggressiveness through miR-183- and miR-33a-mediated cell cycle regulation.JARID1B Enables Transit between Distinct States of the Stem-like Cell Population in Oral CancersSUMOylation negatively modulates target gene occupancy of the KDM5B, a histone lysine demethylase.The proto-oncogene Myc drives expression of the NK cell-activating NKp30 ligand B7-H6 in tumor cells.TFAP2C expression in breast cancer: correlation with overall survival beyond 10 years of initial diagnosis.Molecular mechanisms of OLIG2 transcription factor in brain cancer.Transcriptional regulation by the AP-2 (TFAP2) family of transcription factorsTFAP2 (AP-2) family regulates transcription of cell cycle factorsJARID1 Histone Demethylases: Emerging Targets in Cancer.Targeting glioma stem-like cell survival and chemo-resistance through inhibition of lysine-specific histone demethylase KDM2B.Effects of alcohol on c-Myc protein in the brain.TransCONFIRM: Identification of a Genetic Signature of Response to Fulvestrant in Advanced Hormone Receptor-Positive Breast Cancer.Targeting Histone Demethylases in MYC-Driven Neuroblastomas with Ciclopirox.TFAP2C homodimer binds MYC and KDM5BTFAP2C homodimer binds the CDKN1A (p21) gene promoterCDKN1A gene expression is stimulated by TFAP2A and repressed by TFAP2CTFAP2C regulates transcription in human naive pluripotency by opening enhancers.Characterization of brain tumor initiating cells isolated from an animal model of CNS primitive neuroectodermal tumors.JMJD5 regulates cell cycle and pluripotency in human embryonic stem cells.
P2860
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P2860
Histone demethylase KDM5B collaborates with TFAP2C and Myc to repress the cell cycle inhibitor p21(cip) (CDKN1A).
description
2012 nî lūn-bûn
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2012年の論文
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2012年学术文章
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2012年学术文章
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2012年学术文章
@zh-hans
2012年学术文章
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2012年学术文章
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2012年學術文章
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2012年學術文章
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2012年學術文章
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name
Histone demethylase KDM5B coll ...... s the cell cycle inhibitor p21
@nl
Histone demethylase KDM5B coll ...... e inhibitor p21(cip) (CDKN1A).
@en
type
label
Histone demethylase KDM5B coll ...... s the cell cycle inhibitor p21
@nl
Histone demethylase KDM5B coll ...... e inhibitor p21(cip) (CDKN1A).
@en
prefLabel
Histone demethylase KDM5B coll ...... s the cell cycle inhibitor p21
@nl
Histone demethylase KDM5B coll ...... e inhibitor p21(cip) (CDKN1A).
@en
P2093
P2860
P356
P1476
Histone demethylase KDM5B coll ...... e inhibitor p21(cip) (CDKN1A).
@en
P2093
Angelo G Scibetta
Chiara Berlato
Fabrizio Miranda
Helen C Hurst
KaYi V Chan
Ping-Pui Wong
P2860
P304
P356
10.1128/MCB.06373-11
P407
P577
2012-02-27T00:00:00Z