Nuclear import of hTERT requires a bipartite nuclear localization signal and Akt-mediated phosphorylation.
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Role of Telomerase in the Cardiovascular SystemThe role of the JAK-STAT pathway and related signal cascades in telomerase activation during the development of hematologic malignanciesThe Velvet Family of Fungal Regulators Contains a DNA-Binding Domain Structurally Similar to NF-κBImplications of telomeres and telomerase in endometrial pathologyTelomerase Regulation from Beginning to the EndHuman telomerase: biogenesis, trafficking, recruitment, and activation.Akt regulates TPP1 homodimerization and telomere protection.Importin 7 and Nup358 promote nuclear import of the protein component of human telomerase.Protein folding as a driving force for dual protein targeting in eukaryotesInhibition of hTERT/telomerase contributes to the antitumor activity of pristimerin in pancreatic ductal adenocarcinoma cells.Fucoidan Induces ROS-Dependent Apoptosis in 5637 Human Bladder Cancer Cells by Downregulating Telomerase Activity via Inactivation of the PI3K/Akt Signaling Pathway.The Selenocysteine-Specific Elongation Factor Contains Unique Sequences That Are Required for Both Nuclear Export and Selenocysteine Incorporation.Perifosine as a potential novel anti-telomerase therapy.Critical Role for Telomerase in the Mechanism of Flow-Mediated Dilation in the Human Microcirculation.Telomerase reverse transcriptase (TERT) is a therapeutic target of oleanane triterpenoid CDDO-Me in prostate cancerInhibition of telomerase activity by oleanane triterpenoid CDDO-Me in pancreatic cancer cells is ROS-dependent.The role of telomeres and telomerase reverse transcriptase isoforms in pluripotency induction and maintenanceIdentification of the nuclear localisation signal of O-GlcNAc transferase and its nuclear import regulation.Targeting EBV-LMP1 DNAzyme enhances radiosensitivity of nasopharyngeal carcinoma cells by inhibiting telomerase activity.Structure-function relationship and biogenesis regulation of the human telomerase holoenzyme.Towards an understanding of regulating Cajal body activity by protein modification.Friend or foe? Telomerase as a pharmacological target in cancer and cardiovascular disease.PI3K/Akt/uncoupling protein 2 signaling pathway may be involved in cell senescence and apoptosis induced by angiotensin II in human vascular endothelial cells.DNA-PKcs-interacting protein KIP binding to TRF2 is required for the maintenance of functional telomeres.Means to the ends: The role of telomeres and telomere processing machinery in metastasis.Radiation-induced upregulation of telomerase activity escapes PI3-kinase inhibition in two malignant glioma cell lines.IFN-α inhibits telomerase in human CD8⁺ T cells by both hTERT downregulation and induction of p38 MAPK signaling.Hsp90-binding immunophilin FKBP51 forms complexes with hTERT enhancing telomerase activity.Computational identification of post-translational modification-based nuclear import regulations by characterizing nuclear localization signal-import receptor interaction.The PI3K/AKT/mTOR interactive pathway.Structure-function relationships during transgenic telomerase expression in Arabidopsis.NOVA1 regulates hTERT splicing and cell growth in non-small cell lung cancer
P2860
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P2860
Nuclear import of hTERT requires a bipartite nuclear localization signal and Akt-mediated phosphorylation.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
Nuclear import of hTERT requir ...... Akt-mediated phosphorylation.
@en
Nuclear import of hTERT requir ...... Akt-mediated phosphorylation.
@nl
type
label
Nuclear import of hTERT requir ...... Akt-mediated phosphorylation.
@en
Nuclear import of hTERT requir ...... Akt-mediated phosphorylation.
@nl
prefLabel
Nuclear import of hTERT requir ...... Akt-mediated phosphorylation.
@en
Nuclear import of hTERT requir ...... Akt-mediated phosphorylation.
@nl
P2093
P356
P1476
Nuclear import of hTERT requir ...... Akt-mediated phosphorylation.
@en
P2093
In Kwon Chung
Jeeyun Chung
Prabhat Khadka
P304
P356
10.1242/JCS.099267
P407
P577
2012-02-24T00:00:00Z