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Assembly of a Fab1 phosphoinositide kinase signaling complex requires the Fig4 phosphoinositide phosphataseThe Fab1/PIKfyve phosphoinositide phosphate kinase is not necessary to maintain the pH of lysosomes and of the yeast vacuole.Atg18 regulates organelle morphology and Fab1 kinase activity independent of its membrane recruitment by phosphatidylinositol 3,5-bisphosphateFelic (CIP4b), a novel binding partner with the Src kinase Lyn and Cdc42, localizes to the phagocytic cupAn electrostatic switch displaces phosphatidylinositol phosphate kinases from the membrane during phagocytosis.Phagosome maturation: a few bugs in the system.The Fab1 phosphatidylinositol kinase pathway in the regulation of vacuole morphology.Critical role for scaffolding adapter Gab2 in Fc gamma R-mediated phagocytosismTOR controls lysosome tubulation and antigen presentation in macrophages and dendritic cells.Localized diacylglycerol-dependent stimulation of Ras and Rap1 during phagocytosis.The acyltransferase LYCAT controls specific phosphoinositides and related membrane traffic.Phosphatidylinositol-3,5-bisphosphate: no longer the poor PIP2.Quantifying Phagocytosis by Immunofluorescence and Microscopy.The Phosphoinositide-Gated Lysosomal Ca(2+) Channel, TRPML1, Is Required for Phagosome Maturation.PIKfyve inhibition interferes with phagosome and endosome maturation in macrophages.Phagocytosis: Hungry, Hungry Cells.The big and intricate dreams of little organelles: Embracing complexity in the study of membrane traffic.Vac14 protein multimerization is a prerequisite step for Fab1 protein complex assembly and functionThe Lipid Kinase PIKfyve Coordinates the Neutrophil Immune Response through the Activation of the Rac GTPase.Phagocytosis Enhances Lysosomal and Bactericidal Properties by Activating the Transcription Factor TFEB.Indirect role for COPI in the completion of FCgamma receptor-mediated phagocytosis.Role of COPI in phagosome maturation.The genomic structure of SYCP3, a meiosis-specific gene encoding a protein of the chromosome core.Phosphoinositide Diversity, Distribution, and Effector Function: Stepping Out of the Box.Radiolabeling and Quantification of Cellular Levels of Phosphoinositides by High Performance Liquid Chromatography-coupled Flow Scintillation.Selective regulation of clathrin-mediated epidermal growth factor receptor signaling and endocytosis by phospholipase C and calcium.pH of endophagosomes controls association of their membranes with Vps34 and PtdIns(3)P levels.Lysosome remodelling and adaptation during phagocyte activation.Quantitative Immunofluorescence to Study Phagosome Maturation.Lysosome enlargement during inhibition of the lipid kinase PIKfyve proceeds through lysosome coalescence.Changing phosphoinositides "on the fly": how trafficking vesicles avoid an identity crisis.The PH domain from the Toxoplasma gondii PH-containing protein-1 (TgPH1) serves as an ectopic reporter of phosphatidylinositol 3-phosphate in mammalian cells.BioEssays in phosphoinositides: A special collectionPhagosomal Maturation, Acidification, and Inhibition of Bacterial Growth in Nonphagocytic Cells Transfected with FcγRIIA ReceptorsLysophosphatidic acid represses autophagy in prostate carcinoma cellsPhagocytosis: what's on the menu? 1Enhanced translation expands the endo-lysosome size and promotes antigen presentation during phagocyte activationLysosome Fission: Planning for an ExitIron overload inhibits late stage autophagic flux leading to insulin resistance
P50
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P50
description
hulumtues
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Roberto J Botelho
@nl
Roberto J Botelho
@sl
Roberto J. Botelho
@en
Roberto J. Botelho
@es
type
label
Roberto J Botelho
@nl
Roberto J Botelho
@sl
Roberto J. Botelho
@en
Roberto J. Botelho
@es
prefLabel
Roberto J Botelho
@nl
Roberto J Botelho
@sl
Roberto J. Botelho
@en
Roberto J. Botelho
@es
P1053
B-9145-2013
P106
P1153
7003913029
P21
P31
P3829
P3835
roberto-botelho
P496
0000-0002-7820-0999