ERK1 and ERK2 regulate embryonic stem cell self-renewal through phosphorylation of Klf4.
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The Importance of Ubiquitination and Deubiquitination in Cellular ReprogrammingMolecular basis of embryonic stem cell self-renewal: from signaling pathways to pluripotency networkCell type-dependent Erk-Akt pathway crosstalk regulates the proliferation of fetal neural progenitor cellsKnowledge-Based Analysis for Detecting Key Signaling Events from Time-Series Phosphoproteomics Data.Fine-tuning of iPSC derivation by an inducible reprogramming system at the protein level.KLF4 is regulated by RAS/RAF/MEK/ERK signaling through E2F1 and promotes melanoma cell growth.Autocrine FGF feedback can establish distinct states of Nanog expression in pluripotent stem cells: a computational analysis.Concise review: a high-content screening approach to stem cell research and drug discovery.Combining small molecules for cell reprogramming through an interatomic analysis.Sox2 expression is regulated by a negative feedback loop in embryonic stem cells that involves AKT signaling and FoxO1.MicroRNA modulation induced by AICA ribonucleotide in J1 mouse ES cellsTAM receptor deficiency affects adult hippocampal neurogenesis.Differentiation-Dependent KLF4 Expression Promotes Lytic Epstein-Barr Virus Infection in Epithelial CellsPost-Transcriptional Regulation of KLF4 by High-Risk Human Papillomaviruses Is Necessary for the Differentiation-Dependent Viral Life Cycle.Secreted Ephrin Receptor A7 Promotes Somatic Cell Reprogramming by Inducing ERK Activity ReductionFBXO32 suppresses breast cancer tumorigenesis through targeting KLF4 to proteasomal degradation.Erk signaling is indispensable for genomic stability and self-renewal of mouse embryonic stem cells.F-box protein FBXO22 mediates polyubiquitination and degradation of KLF4 to promote hepatocellular carcinoma progression.MicroRNA-7 inhibits the stemness of prostate cancer stem-like cells and tumorigenesis by repressing KLF4/PI3K/Akt/p21 pathwaySide population in hepatocellular carcinoma HCCLM3 cells is enriched with stem-like cancer cells.ERK2 phosphorylates Krüppel-like factor 8 protein at serine 48 to maintain its stability.EIF2S3Y suppresses the pluripotency state and promotes the proliferation of mouse embryonic stem cellsThe deubiquitinase USP21 maintains the stemness of mouse embryonic stem cells via stabilization of Nanog.Regulation of estrogen receptor signaling in breast carcinogenesis and breast cancer therapy.The voyage of stem cell toward terminal differentiation: a brief overview.Post-translational modulation of pluripotency.Convergent mechanisms in pluripotent stem cells and cancer: implications for stem cell engineering.Protein kinases and associated pathways in pluripotent state and lineage differentiation.SUMOylation of KLF4 promotes IL-4 induced macrophage M2 polarization.Role of the reprogramming factor KLF4 in blood formation.Krüppel-like factors in mammalian stem cells and development.p21 and CK2 interaction-mediated HDAC2 phosphorylation modulates KLF4 acetylation to regulate bladder cancer cell proliferation.Krüppel-like factor 4 (KLF4): What we currently know.Emerging role of DUBs in tumor metastasis and apoptosis: Therapeutic implication.Capturing Human Naïve Pluripotency in the Embryo and in the Dish.TAM receptors: two pathways to regulate adult neurogenesis.Does mouse embryo primordial germ cell activation start before implantation as suggested by single-cell transcriptomics dynamics?Regulation of Nucleosome Architecture and Factor Binding Revealed by Nuclease Footprinting of the ESC Genome.BAALC potentiates oncogenic ERK pathway through interactions with MEKK1 and KLF4.Maintenance of Self-Renewal and Pluripotency in J1 Mouse Embryonic Stem Cells through Regulating Transcription Factor and MicroRNA Expression Induced by PD0325901.
P2860
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P2860
ERK1 and ERK2 regulate embryonic stem cell self-renewal through phosphorylation of Klf4.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
ERK1 and ERK2 regulate embryonic stem cell self-renewal through phosphorylation of Klf4.
@en
ERK1 and ERK2 regulate embryonic stem cell self-renewal through phosphorylation of Klf4.
@nl
type
label
ERK1 and ERK2 regulate embryonic stem cell self-renewal through phosphorylation of Klf4.
@en
ERK1 and ERK2 regulate embryonic stem cell self-renewal through phosphorylation of Klf4.
@nl
prefLabel
ERK1 and ERK2 regulate embryonic stem cell self-renewal through phosphorylation of Klf4.
@en
ERK1 and ERK2 regulate embryonic stem cell self-renewal through phosphorylation of Klf4.
@nl
P2093
P2860
P921
P356
P1476
ERK1 and ERK2 regulate embryonic stem cell self-renewal through phosphorylation of Klf4
@en
P2093
Ann M Bode
Chul-Ho Jeong
Dong Joon Kim
Dong-Hoon Yu
Janos Nadas
Kun-Yeong Lee
Myoung Ok Kim
Sung-Hyun Kim
Yong-Yeon Cho
P2860
P2888
P304
P356
10.1038/NSMB.2217
P50
P577
2012-02-05T00:00:00Z