Ca(2+) elevation evoked by membrane depolarization regulates G protein cycle via RGS proteins in the heart.
about
PIP3 inhibition of RGS protein and its reversal by Ca2+/calmodulin mediate voltage-dependent control of the G protein cycle in a cardiac K+ channel.Regulators of G-protein signaling and their Gα substrates: promises and challenges in their use as drug discovery targets.Thinking outside of the "RGS box": new approaches to therapeutic targeting of regulators of G protein signaling.Mechanisms of cross-talk between G-protein-coupled receptors resulting in enhanced release of intracellular Ca2+.RGS3 mediates a calcium-dependent termination of G protein signaling in sensory neurons.Cell signal control of the G protein-gated potassium channel and its subcellular localization.Dopaminergic intracellular signal integrating proteins: relevance to schizophrenia.RGS4 regulates partial agonism of the M2 muscarinic receptor-activated K+ currents.The plasma membrane potential and the organization of the actin cytoskeleton of epithelial cells.G protein-independent inhibition of GIRK current by adenosine in rat atrial myocytes overexpressing A1 receptors after adenovirus-mediated gene transfer.Pharmacological Conversion of a Cardiac Inward Rectifier into an Outward Rectifier Potassium Channel.Structural determinants at the M2 muscarinic receptor modulate the RGS4-GIRK response to pilocarpine by impairment of the receptor voltage sensitivity.RGS Proteins in Heart: Brakes on the Vagus.Short-term desensitization of muscarinic K+ current in the heart.Phosphatidylinositol 3,4,5-trisphosphate and Ca2+/calmodulin competitively bind to the regulators of G-protein-signalling (RGS) domain of RGS4 and reciprocally regulate its actionRegulator of G protein signaling-4 controls fatty acid and glucose homeostasis.Controlling Parasympathetic Regulation of Heart Rate: A Gatekeeper Role for RGS Proteins in the Sinoatrial Node.Cellular modelling: experiments and simulation to develop a physiological model of G-protein control of muscarinic K+ channels in mammalian atrial cells.Transfection of a phosphatidyl-4-phosphate 5-kinase gene into rat atrial myocytes removes inhibition of GIRK current by endothelin and alpha-adrenergic agonists.I(KACh) at the whim of a capricious M2R.Voltage sensitivity of M2 muscarinic receptors underlies the delayed rectifier-like activation of ACh-gated K(+) current by choline in feline atrial myocytes.
P2860
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P2860
Ca(2+) elevation evoked by membrane depolarization regulates G protein cycle via RGS proteins in the heart.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
2001年论文
@zh
2001年论文
@zh-cn
name
Ca(2+) elevation evoked by mem ...... via RGS proteins in the heart.
@en
type
label
Ca(2+) elevation evoked by mem ...... via RGS proteins in the heart.
@en
prefLabel
Ca(2+) elevation evoked by mem ...... via RGS proteins in the heart.
@en
P2093
P356
P1433
P1476
Ca(2+) elevation evoked by mem ...... via RGS proteins in the heart.
@en
P2093
P304
P356
10.1161/HH2301.100815
P577
2001-11-01T00:00:00Z