Proteostasis of tau. Tau overexpression results in its secretion via membrane vesicles.
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Paired helical filaments from Alzheimer disease brain induce intracellular accumulation of Tau protein in aggresomesIs tau ready for admission to the prion club?Focus on Extracellular Vesicles: Exosomes and Their Role in Protein Trafficking and Biomarker Potential in Alzheimer's and Parkinson's DiseaseMyeloid Extracellular Vesicles: Messengers from the Demented BrainTangles, Toxicity, and Tau Secretion in AD - New Approaches to a Vexing ProblemProteolytic clearance of extracellular α-synuclein as a new therapeutic approach against Parkinson diseasePrion-like properties of Tau protein: the importance of extracellular Tau as a therapeutic targetImpact of lysosome status on extracellular vesicle content and releaseAlpha-synuclein and tau: teammates in neurodegeneration?The release and trans-synaptic transmission of Tau via exosomesExtracellular Vesicles as a Source of Urological Biomarkers: Lessons Learned From Advances and Challenges in Clinical Applications to Major Diseases.Hyperphosphorylation and cleavage at D421 enhance tau secretionCharacterization of novel CSF Tau and ptau biomarkers for Alzheimer's disease.Expression of Tau40 induces activation of cultured rat microglial cells.A network of RNA and protein interactions in Fronto Temporal Dementia.Ectosomes: a new mechanism for non-exosomal secretion of tau protein.Increased levels of cerebrospinal fluid JNK3 associated with amyloid pathology: links to cognitive decline.The Ambiguous Relationship of Oxidative Stress, Tau Hyperphosphorylation, and Autophagy Dysfunction in Alzheimer's Disease.Potential contribution of exosomes to the prion-like propagation of lesions in Alzheimer's disease.Tau secretion is correlated to an increase of Golgi dynamics.Extracellular Tau levels are influenced by variability in Tau that is associated with tauopathies.Exosomes, an Unmasked Culprit in Neurodegenerative Diseases.The role of extracellular Tau in the spreading of neurofibrillary pathology.Looking for novel functions of tau.Cellular mechanisms of protein aggregate propagationSpreading of tau pathology in Alzheimer's disease by cell-to-cell transmission.Propagation of tau pathology in Alzheimer's disease: identification of novel therapeutic targets.Further understanding of tau phosphorylation: implications for therapy.Prions and Protein Assemblies that Convey Biological Information in Health and Disease.Extracellular vesicles in Alzheimer's disease: friends or foes? Focus on aβ-vesicle interaction.Mutant huntingtin is secreted via a late endosomal/lysosomal unconventional secretory pathway.A Simple Model to Study Tau Pathology.Intracellular and extracellular microtubule associated protein tau as a therapeutic target in Alzheimer disease and other tauopathies.Horizontal Transmission of Cytosolic Sup35 Prions by Extracellular VesiclesExtracellular association of APP and tau fibrils induces intracellular aggregate formation of tau.Prion-like propagation as a pathogenic principle in frontotemporal dementia.Sphingolipid-Enriched Extracellular Vesicles and Alzheimer's Disease: A Decade of Research.Proteins recruited to exosomes by tau overexpression implicate novel cellular mechanisms linking tau secretion with Alzheimer's disease.Extracellular monomeric tau protein is sufficient to initiate the spread of tau protein pathology.Physiological release of endogenous tau is stimulated by neuronal activity.
P2860
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P2860
Proteostasis of tau. Tau overexpression results in its secretion via membrane vesicles.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年学术文章
@wuu
2011年学术文章
@zh-cn
2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
@yue
2011年學術文章
@zh
2011年學術文章
@zh-hant
name
Proteostasis of tau. Tau overexpression results in its secretion via membrane vesicles.
@en
Proteostasis of tau. Tau overexpression results in its secretion via membrane vesicles.
@nl
type
label
Proteostasis of tau. Tau overexpression results in its secretion via membrane vesicles.
@en
Proteostasis of tau. Tau overexpression results in its secretion via membrane vesicles.
@nl
prefLabel
Proteostasis of tau. Tau overexpression results in its secretion via membrane vesicles.
@en
Proteostasis of tau. Tau overexpression results in its secretion via membrane vesicles.
@nl
P2860
P50
P1433
P1476
Proteostasis of tau. Tau overexpression results in its secretion via membrane vesicles
@en
P2093
Esther García-García
Felix Royo
P2860
P356
10.1016/J.FEBSLET.2011.11.022
P407
P577
2011-11-28T00:00:00Z