Sulfonyl fluorides as privileged warheads in chemical biology
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Multidimensional SuFEx Click Chemistry: Sequential Sulfur(VI) Fluoride Exchange Connections of Diverse Modules Launched From An SOF4 Hub.A library approach to rapidly discover photoaffinity probes of the mRNA decapping scavenger enzyme DcpS.Broad-Spectrum Kinase Profiling in Live Cells with Lysine-Targeted Sulfonyl Fluoride Probes.A covalent antagonist for the human adenosine A2A receptor.One-pot palladium-catalyzed synthesis of sulfonyl fluorides from aryl bromides.Binding site elucidation and structure guided design of macrocyclic IL-17A antagonists.An Irreversible Inhibitor of HSP72 that Unexpectedly Targets Lysine-56A Heck-Matsuda Process for the Synthesis of β-Arylethenesulfonyl Fluorides: Selectively Addressable Bis-electrophiles for SuFEx Click Chemistry.Expanding the Scope of Electrophiles Capable of Targeting K-Ras Oncogenes.Combining Click Sulfur(VI)-Fluoride Exchange with Photoiniferters: A Facile, Fast, and Efficient Strategy for Postpolymerization Modification.A study of the reactivity of S(VI)-F containing warheads with nucleophilic amino-acid side chains under physiological conditions.A Vinyl Sulfone-Based Fluorogenic Probe Capable of Selective Labeling of PHGDH in Live Mammalian Cells.Identification of cross-reactive B-cell epitopes between Bos d 9.0101(Bos Taurus) and Gly m 5.0101 (Glycine max) by epitope mapping MALDI-TOF MS.SuFEx Chemistry of Thionyl Tetrafluoride (SOF4 ) with Organolithium Nucleophiles: Synthesis of Sulfonimidoyl Fluorides, Sulfoximines, Sulfonimidamides, and Sulfonimidates.Chemoselective Preparation of Clickable Aryl Sulfonyl Fluoride Monomers: A Toolbox of Highly Functionalized Intermediates for Chemical Biology Probe Synthesis.Tunable Probes with Direct Fluorescence Signals for the Constitutive and Immunoproteasome.Fluorescence switchable probes based on a molecular rotor for selective detection of proteins and small molecules.Modification of Amino Groups.A covalent G-site inhibitor for glutathione S-transferase Pi (GSTP1-1).Genetically Encoding Fluorosulfate-l-tyrosine To React with Lysine, Histidine, and Tyrosine via SuFEx in Proteins in Vivo.Cellular thermal shift and clickable chemical probe assays for the determination of drug-target engagement in live cellsUnderstanding the chemically-reactive proteomeChemInform Abstract: Sulfonyl Fluorides as Privileged Warheads in Chemical BiologyCharacterization of ML-005, a Novel Metaproteomics-Derived EsteraseAn Affinity-Based Probe for the Human Adenosine A Receptor
P2860
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P2860
Sulfonyl fluorides as privileged warheads in chemical biology
description
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Sulfonyl fluorides as privileged warheads in chemical biology
@en
Sulfonyl fluorides as privileged warheads in chemical biology.
@nl
type
label
Sulfonyl fluorides as privileged warheads in chemical biology
@en
Sulfonyl fluorides as privileged warheads in chemical biology.
@nl
prefLabel
Sulfonyl fluorides as privileged warheads in chemical biology
@en
Sulfonyl fluorides as privileged warheads in chemical biology.
@nl
P2860
P356
P1433
P1476
Sulfonyl fluorides as privileged warheads in chemical biology
@en
P2093
Arjun Narayanan
P2860
P304
P356
10.1039/C5SC00408J
P50
P577
2015-03-16T00:00:00Z