Structure-activity relationships of pentamidine-affected ion channel trafficking and dofetilide mediated rescue.
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Translational toxicology and rescue strategies of the hERG channel dysfunction: biochemical and molecular mechanistic aspectsQuantitative Profiling of the Effects of Vanoxerine on Human Cardiac Ion Channels and its Application to Cardiac Risk.A 2015 focus on preventing drug-induced arrhythmias.PA-6 inhibits inward rectifier currents carried by V93I and D172N gain-of-function KIR2.1 channels, but increases channel protein expression.Class III antiarrhythmic drugs amiodarone and dronedarone impair KIR 2.1 backward trafficking.Computational Modeling of Electrophysiology and Pharmacotherapy of Atrial Fibrillation: Recent Advances and Future ChallengesCommentary: Golgin-97 Targets Ectopically Expressed Inward Rectifying Potassium Channel, Kir2.1, to the -Golgi Network in COS-7 Cells
P2860
Q27008208-2E1F4194-4D7D-4450-9873-ACD955E6696DQ36329486-965435C2-0461-4BB7-9767-599D1AE77560Q38631174-1EC8EB4A-C02D-4437-AD55-7EB973E1D24EQ41033530-8672A40F-3B1F-4567-8369-08F4BBE66B95Q42365788-0379A3F2-3317-4937-9F6D-BE5FAE0A8CBBQ57161239-EF110C91-F73A-4078-BEAB-42F4C44B8641Q57818033-9BF51C8E-B6D9-40B0-B80B-66F2B2076821
P2860
Structure-activity relationships of pentamidine-affected ion channel trafficking and dofetilide mediated rescue.
description
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name
Structure-activity relationshi ...... nd dofetilide mediated rescue.
@en
Structure-activity relationshi ...... nd dofetilide mediated rescue.
@nl
type
label
Structure-activity relationshi ...... nd dofetilide mediated rescue.
@en
Structure-activity relationshi ...... nd dofetilide mediated rescue.
@nl
prefLabel
Structure-activity relationshi ...... nd dofetilide mediated rescue.
@en
Structure-activity relationshi ...... nd dofetilide mediated rescue.
@nl
P2093
P2860
P356
P1476
Structure-activity relationshi ...... nd dofetilide mediated rescue.
@en
P2093
A P Ijzerman
A Stary-Weinzinger
H D M Beekman
K C G de Git
M A G van der Heyden
M J C Houtman
R R Tidwell
R Varkevisser
P2860
P304
P356
10.1111/BPH.12208
P407
P577
2013-07-01T00:00:00Z