Depletion of GRIM-19 accelerates hepatocellular carcinoma invasion via inducing EMT and loss of contact inhibition.
about
Overexpression of GRIM-19, a mitochondrial respiratory chain complex I protein, suppresses hepatocellular carcinoma growth.Decreased expression of GRIM-19 by DNA hypermethylation promotes aerobic glycolysis and cell proliferation in head and neck squamous cell carcinoma.Tumor-derived mutations in the gene associated with retinoid interferon-induced mortality (GRIM-19) disrupt its anti-signal transducer and activator of transcription 3 (STAT3) activity and promote oncogenesis.Monoallelic loss of tumor suppressor GRIM-19 promotes tumorigenesis in mice.GRIM-19: A master regulator of cytokine induced tumor suppression, metastasis and energy metabolism.HBx-dependent activation of Twist mediates STAT3 control of epithelium-mesenchymal transition of liver cells.MicroRNA-491 is involved in metastasis of hepatocellular carcinoma by inhibitions of matrix metalloproteinase and epithelial to mesenchymal transition.
P2860
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P2860
Depletion of GRIM-19 accelerates hepatocellular carcinoma invasion via inducing EMT and loss of contact inhibition.
description
2012 nî lūn-bûn
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2012年の論文
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2012年学术文章
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2012年学术文章
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2012年学术文章
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2012年学术文章
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2012年学术文章
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2012年學術文章
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name
Depletion of GRIM-19 accelerat ...... nd loss of contact inhibition.
@en
Depletion of GRIM-19 accelerat ...... nd loss of contact inhibition.
@nl
type
label
Depletion of GRIM-19 accelerat ...... nd loss of contact inhibition.
@en
Depletion of GRIM-19 accelerat ...... nd loss of contact inhibition.
@nl
prefLabel
Depletion of GRIM-19 accelerat ...... nd loss of contact inhibition.
@en
Depletion of GRIM-19 accelerat ...... nd loss of contact inhibition.
@nl
P2093
P2860
P356
P1476
Depletion of GRIM-19 accelerat ...... nd loss of contact inhibition.
@en
P2093
Dongshi Guan
Guoliang Liu
Hongbo Hao
Xinmin Cao
Xiuqing Zhang
P2860
P304
P356
10.1002/JCP.24025
P577
2012-03-01T00:00:00Z