The influenza virus PB1-F2 protein has interferon antagonistic activity.
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Toscana virus NSs protein inhibits the induction of type I interferon by interacting with RIG-IEvidence for a Novel Mechanism of Influenza Virus-Induced Type I Interferon Expression by a Defective RNA-Encoded ProteinActivation of the NLRP3 inflammasome by IAV virulence protein PB1-F2 contributes to severe pathophysiology and diseaseInfluenza virus activation of the interferon systemInfluenza A virus PB1-F2 protein expression is regulated in a strain-specific manner by sequences located downstream of the PB1-F2 initiation codon.Molecular determinants of influenza virus pathogenesis in mice.Interactions between the influenza A virus RNA polymerase components and retinoic acid-inducible gene I.Highly pathogenic H5N1 influenza A virus strains provoke heterogeneous IFN-α/β responses that distinctively affect viral propagation in human cells.Kinetic characterization of PB1-F2-mediated immunopathology during highly pathogenic avian H5N1 influenza virus infectionComputational analysis and mapping of novel open reading frames in influenza A viruses.The influenza virus protein PB1-F2 interacts with IKKβ and modulates NF-κB signalling.The ubiquitination of the influenza A virus PB1-F2 protein is crucial for its biological functionEmergence of Highly Pathogenic Avian Influenza A(H5N1) Virus PB1-F2 Variants and Their Virulence in BALB/c Mice.Naturally occurring swine influenza A virus PB1-F2 phenotypes that contribute to superinfection with Gram-positive respiratory pathogensStrain-dependent effects of PB1-F2 of triple-reassortant H3N2 influenza viruses in swine.Inflammatory response of mast cells during influenza A virus infection is mediated by active infection and RIG-I signaling.A novel cytotoxic sequence contributes to influenza A viral protein PB1-F2 pathogenicity and predisposition to secondary bacterial infection.Induction and evasion of type I interferon responses by influenza viruses.Variability among the neuraminidase, non-structural 1 and PB1-F2 proteins in the influenza A virus genome.Evasion of influenza A viruses from innate and adaptive immune responses.Single-cell studies of IFN-β promoter activation by wild-type and NS1-defective influenza A viruses.Phosphorylation of influenza A virus NS1 protein at threonine 49 suppresses its interferon antagonistic activity.An unbiased genetic screen reveals the polygenic nature of the influenza virus anti-interferon response.H5N1 influenza virulence, pathogenicity and transmissibility: what do we know?Super-infection with Staphylococcus aureus inhibits influenza virus-induced type I IFN signalling through impaired STAT1-STAT2 dimerization.PB1-F2 modulates early host responses but does not affect the pathogenesis of H1N1 seasonal influenza virus.Influenza A viruses suppress cyclooxygenase-2 expression by affecting its mRNA stability.RIG-I Activation Protects and Rescues from Lethal Influenza Virus Infection and Bacterial Superinfection.Analysis of the phylogeny of Chinese H9N2 avian influenza viruses and their pathogenicity in mice.Evolution and Virulence of Influenza A Virus Protein PB1-F2.Virulent PB1-F2 residues: effects on fitness of H1N1 influenza A virus in mice and changes during evolution of human influenza A viruses.
P2860
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P2860
The influenza virus PB1-F2 protein has interferon antagonistic activity.
description
2011 nî lūn-bûn
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2011年の論文
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2011年学术文章
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2011年学术文章
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2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
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2011年學術文章
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name
The influenza virus PB1-F2 protein has interferon antagonistic activity.
@en
The influenza virus PB1-F2 protein has interferon antagonistic activity.
@nl
type
label
The influenza virus PB1-F2 protein has interferon antagonistic activity.
@en
The influenza virus PB1-F2 protein has interferon antagonistic activity.
@nl
prefLabel
The influenza virus PB1-F2 protein has interferon antagonistic activity.
@en
The influenza virus PB1-F2 protein has interferon antagonistic activity.
@nl
P2093
P2860
P356
P1433
P1476
The influenza virus PB1-F2 protein has interferon antagonistic activity.
@en
P2093
Alexandra Nordmann
Carolin Nordhoff
Darisuren Anhlan
Ludmilla Wixler
Sabine E Dudek
Viktor Wixler
P2860
P304
P356
10.1515/BC.2011.174
P577
2011-12-01T00:00:00Z