Massive apoptosis of thymocytes in T-cell-deficient Id1 transgenic mice.
about
Functions of E2A-HEB heterodimers in T-cell development revealed by a dominant negative mutation of HEBmSin3A regulates murine erythroleukemia cell differentiation through association with the TAL1 (or SCL) transcription factorAbundant expression of Dec1/stra13/sharp2 in colon carcinoma: its antagonizing role in serum deprivation-induced apoptosis and selective inhibition of procaspase activationHEB in the spotlight: Transcriptional regulation of T-cell specification, commitment, and developmental plasticityGradient of E2A activity in B-cell development.TGF-beta repression of Id2 induces apoptosis in gut epithelial cellsId2 intrinsically regulates lymphoid and erythroid development via interaction with different target proteinsRegulation of the helix-loop-helix proteins, E2A and Id3, by the Ras-ERK MAPK cascade.A mechanism misregulating p27 in tumors discovered in a functional genomic screen.Id1 induces apoptosis through inhibition of RORgammat expressionHes1 potentiates T cell lymphomagenesis by up-regulating a subset of notch target genes.Id1 expression promotes T regulatory cell differentiation by facilitating TCR costimulation.Increased expression of Id1 and Id3 promotes tumorigenicity by enhancing angiogenesis and suppressing apoptosis in small cell lung cancerRepression of Id2 expression by Gfi-1 is required for B-cell and myeloid developmentIntertwining proteins in thymocyte development and cancer.Enhanced Notch activation is advantageous but not essential for T cell lymphomagenesis in Id1 transgenic miceTranscriptional control of t lymphocyte differentiation.E proteins and the regulation of early lymphocyte developmentE2A-HLF usurps control of evolutionarily conserved survival pathways.Role of Id family proteins in growth control.The function of E- and Id proteins in lymphocyte development.Diverse roles of inhibitor of differentiation 2 in adaptive immunity.SCL, LMO1 and Notch1 reprogram thymocytes into self-renewing cellsId1 immortalizes hematopoietic progenitors in vitro and promotes a myeloproliferative disease in vivoLineage plasticity and commitment in T-cell development.Surviving the crash: transitioning from effector to memory CD8+ T cell.The t(14;21)(q11.2;q22) chromosomal translocation associated with T-cell acute lymphoblastic leukemia activates the BHLHB1 geneHuman T-cell leukemia virus type 1 Tax protein down-regulates pre-T-cell receptor alpha gene transcription in human immature thymocytesCommitment to natural killer cells requires the helix-loop-helix inhibitor Id2Id1, but not Id3, directs long-term repopulating hematopoietic stem-cell maintenance.Helix-loop-helix proteins and lymphocyte development.Inhibitor of differentiation 1 transcription factor promotes metabolic reprogramming in hepatocellular carcinoma cells.E2A promotes the survival of precursor and mature B lymphocytes.E2A and HEB are required to block thymocyte proliferation prior to pre-TCR expression.Id1 cooperates with oncogenic Ras to induce metastatic mammary carcinoma by subversion of the cellular senescence response.Overexpression of Id-1 is significantly associated with tumour angiogenesis in human pancreas cancers.Inflammatory properties of inhibitor of DNA binding 1 secreted by synovial fibroblasts in rheumatoid arthritis.Bone marrow and peripheral blood expression of ID1 in human gastric carcinoma patients is a bona fide indicator of lymph node and peritoneal metastasis.Id1 attenuates Notch signaling and impairs T-cell commitment by elevating Deltex1 expression.Hyperresponse to T-cell receptor signaling and apoptosis of Id1 transgenic thymocytes.
P2860
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P2860
Massive apoptosis of thymocytes in T-cell-deficient Id1 transgenic mice.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh
1999年學術文章
@zh-hant
name
Massive apoptosis of thymocytes in T-cell-deficient Id1 transgenic mice.
@en
Massive apoptosis of thymocytes in T-cell-deficient Id1 transgenic mice.
@nl
type
label
Massive apoptosis of thymocytes in T-cell-deficient Id1 transgenic mice.
@en
Massive apoptosis of thymocytes in T-cell-deficient Id1 transgenic mice.
@nl
prefLabel
Massive apoptosis of thymocytes in T-cell-deficient Id1 transgenic mice.
@en
Massive apoptosis of thymocytes in T-cell-deficient Id1 transgenic mice.
@nl
P2093
P2860
P356
P1476
Massive apoptosis of thymocytes in T-cell-deficient Id1 transgenic mice.
@en
P2093
P2860
P304
P356
10.1128/MCB.19.12.8240
P407
P577
1999-12-01T00:00:00Z