v-Jun overrides the mitogen dependence of S-phase entry by deregulating retinoblastoma protein phosphorylation and E2F-pocket protein interactions as a consequence of enhanced cyclin E-cdk2 catalytic activity.
about
A new c-Jun N-terminal kinase (JNK)-interacting protein, Sab (SH3BP5), associates with mitochondriaDominant negative c-jun inhibits activation of the cyclin D1 and cyclin E kinase complexesRETRACTED: Inactivation of MAP kinase signalling in Myc transformed cells and rescue by LiCl inhibition of GSK3.Distinct roles of Jun : Fos and Jun : ATF dimers in oncogenesisCyclin A is a c-Jun target gene and is necessary for c-Jun-induced anchorage-independent growth in RAT1a cellsxCT expression reduces the early cell cycle requirement for calcium signalingGlobal regulation of genome duplication in eukaryotes: an overview from the epifluorescence microscope.Downregulation of Cdc2/CDK1 kinase activity induces the synthesis of noninfectious human papillomavirus type 31b virions in organotypic tissues exposed to benzo[a]pyrene.Adeno-associated virus type 2 increases proteosome-dependent degradation of p21WAF1 in a human papillomavirus type 31b-positive cervical carcinoma lineSignal transduction mediated by the Ras/Raf/MEK/ERK pathway from cytokine receptors to transcription factors: potential targeting for therapeutic intervention.Identification of cJun-responsive genes in Rat-1a cells using multiple techniques: increased expression of stathmin is necessary for cJun-mediated anchorage-independent growth.Chk1-deficient tumour cells are viable but exhibit multiple checkpoint and survival defects.Chk1-dependent S-M checkpoint delay in vertebrate cells is linked to maintenance of viable replication structures.Accelerated cell cycle progression in osteoblasts overexpressing the c-fos proto-oncogene: induction of cyclin A and enhanced CDK2 activity.Runx2 disruption promotes immortalization and confers resistance to oncogene-induced senescence in primary murine fibroblasts.Microarray analysis identifies Autotaxin, a tumour cell motility and angiogenic factor with lysophospholipase D activity, as a specific target of cell transformation by v-Jun.
P2860
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P2860
v-Jun overrides the mitogen dependence of S-phase entry by deregulating retinoblastoma protein phosphorylation and E2F-pocket protein interactions as a consequence of enhanced cyclin E-cdk2 catalytic activity.
description
2000 nî lūn-bûn
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2000年の論文
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2000年学术文章
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2000年学术文章
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2000年学术文章
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name
v-Jun overrides the mitogen de ...... lin E-cdk2 catalytic activity.
@en
v-Jun overrides the mitogen de ...... lin E-cdk2 catalytic activity.
@nl
type
label
v-Jun overrides the mitogen de ...... lin E-cdk2 catalytic activity.
@en
v-Jun overrides the mitogen de ...... lin E-cdk2 catalytic activity.
@nl
prefLabel
v-Jun overrides the mitogen de ...... lin E-cdk2 catalytic activity.
@en
v-Jun overrides the mitogen de ...... lin E-cdk2 catalytic activity.
@nl
P2093
P2860
P1476
v-Jun overrides the mitogen de ...... clin E-cdk2 catalytic activity
@en
P2093
P2860
P304
P356
10.1128/MCB.20.7.2529-2542.2000
P407
P577
2000-04-01T00:00:00Z