A common motif within the negative regulatory regions of multiple factors inhibits their transcriptional synergy
about
Negative modulation of androgen receptor transcriptional activity by DaxxAssociation with class IIa histone deacetylases upregulates the sumoylation of MEF2 transcription factors.SUMO represses transcriptional activity of the Drosophila SoxNeuro and human Sox3 central nervous system-specific transcription factors.Modification with SUMO. A role in transcriptional regulationStructure and function of steroid receptor AF1 transactivation domains: induction of active conformationsRole for SUMO modification in facilitating transcriptional repression by BKLF.RSUME enhances glucocorticoid receptor SUMOylation and transcriptional activityA conserved lysine in the estrogen receptor DNA binding domain regulates ligand activation profiles at AP-1 sites, possibly by controlling interactions with a modulating repressorCell cycle phase regulates glucocorticoid receptor functionDNA Binding Site Sequence Directs Glucocorticoid Receptor Structure and ActivitySumoylation of MITF and its related family members TFE3 and TFEBA synergy control motif within the attenuator domain of CCAAT/enhancer-binding protein alpha inhibits transcriptional synergy through its PIASy-enhanced modification by SUMO-1 or SUMO-3Transcriptional activity of CCAAT/enhancer-binding proteins is controlled by a conserved inhibitory domain that is a target for sumoylationThe BTB-containing protein Kctd15 is SUMOylated in vivoNF-κB repression by PIAS3 mediated RelA SUMOylationEliminating SF-1 (NR5A1) sumoylation in vivo results in ectopic hedgehog signaling and disruption of endocrine developmentSumoylation of CCAAT/enhancer-binding protein alpha and its functional roles in hepatocyte differentiationSUMO-specific protease 1 (SENP1) reverses the hormone-augmented SUMOylation of androgen receptor and modulates gene responses in prostate cancer cells.Small ubiquitin-like modifier (SUMO) modification of the androgen receptor attenuates polyglutamine-mediated aggregationDisrupting SUMOylation enhances transcriptional function and ameliorates polyglutamine androgen receptor-mediated disease.Sumoylation of the transcription factor NFATc1 leads to its subnuclear relocalization and interleukin-2 repression by histone deacetylasePIAS1 is a GATA4 SUMO ligase that regulates GATA4-dependent intestinal promoters independent of SUMO ligase activity and GATA4 sumoylation.Paired hormone response elements predict caveolin-1 as a glucocorticoid target gene.Crosstalk in inflammation: the interplay of glucocorticoid receptor-based mechanisms and kinases and phosphatasesPhosphorylation-dependent sumoylation regulates estrogen-related receptor-alpha and -gamma transcriptional activity through a synergy control motif.The Role of the Small Ubiquitin-Related Modifier (SUMO) Pathway in Prostate Cancer.Intrinsic disorder in the androgen receptor: identification, characterisation and drugability.Transactivation properties of c-Myb are critically dependent on two SUMO-1 acceptor sites that are conjugated in a PIASy enhanced manner.Sumoylation of Smad4, the common Smad mediator of transforming growth factor-beta family signaling.Control of progesterone receptor transcriptional synergy by SUMOylation and deSUMOylation.Pregnane X receptor is SUMOylated to repress the inflammatory response.PIASgamma represses the transcriptional activation induced by the nuclear receptor Nurr1.Phosphorylated and sumoylation-deficient progesterone receptors drive proliferative gene signatures during breast cancer progressionSumoylation modulates transcriptional activity of MITF in a promoter-specific mannerSUMO-1 modification of human cytomegalovirus IE1/IE72Comparison of TFII-I gene family members deleted in Williams-Beuren syndrome.Sumoylation of the net inhibitory domain (NID) is stimulated by PIAS1 and has a negative effect on the transcriptional activity of Net.Repression of SOX6 transcriptional activity by SUMO modification.Cellular processing of the glucocorticoid receptor gene and protein: new mechanisms for generating tissue-specific actions of glucocorticoids.PIASγ enhanced SUMO-2 modification of Nurr1 activation-function-1 domain limits Nurr1 transcriptional synergy
P2860
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P2860
A common motif within the negative regulatory regions of multiple factors inhibits their transcriptional synergy
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年学术文章
@wuu
2000年学术文章
@zh-cn
2000年学术文章
@zh-hans
2000年学术文章
@zh-my
2000年学术文章
@zh-sg
2000年學術文章
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2000年學術文章
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2000年學術文章
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name
A common motif within the nega ...... their transcriptional synergy
@en
A common motif within the nega ...... their transcriptional synergy.
@nl
type
label
A common motif within the nega ...... their transcriptional synergy
@en
A common motif within the nega ...... their transcriptional synergy.
@nl
prefLabel
A common motif within the nega ...... their transcriptional synergy
@en
A common motif within the nega ...... their transcriptional synergy.
@nl
P2860
P1476
A common motif within the nega ...... their transcriptional synergy
@en
P2093
J A Iñiguez-Lluhí
P2860
P304
P356
10.1128/MCB.20.16.6040-6050.2000
P407
P577
2000-08-01T00:00:00Z