The molecular chaperone activity of simian virus 40 large T antigen is required to disrupt Rb-E2F family complexes by an ATP-dependent mechanism.
about
The retinoblastoma family of proteins and their regulatory functions in the mammalian cell division cycleIdentification of FAM111A as an SV40 host range restriction and adenovirus helper factorTargeting of p300/CREB binding protein coactivators by simian virus 40 is mediated through p53Not all J domains are created equal: implications for the specificity of Hsp40-Hsp70 interactionsSimultaneous application of heat, drought, and virus to Arabidopsis plants reveals significant shifts in signaling networks.Activation of CREB/ATF sites by polyomavirus large T antigen.JC virus T-antigen expression in sporadic adenomatous polyps of the colon.Intestinal dysplasia induced by simian virus 40 T antigen is independent of p53.Mutagenesis of a functional chimeric gene in yeast identifies mutations in the simian virus 40 large T antigen J domain.Merkel cell polyomavirus: molecular insights into the most recently discovered human tumour virus.Discovery of STL polyomavirus, a polyomavirus of ancestral recombinant origin that encodes a unique T antigen by alternative splicing.Transforming functions of Simian Virus 40.Interactions of SV40 large T antigen and other viral proteins with retinoblastoma tumour suppressor.T antigens of simian virus 40: molecular chaperones for viral replication and tumorigenesisSmall tumor antigen of polyomaviruses: role in viral life cycle and cell transformationInhibition of post-transcriptional RNA processing by CDK inhibitors and its implication in anti-viral therapy.The HSP70 modulator MAL3-101 inhibits Merkel cell carcinoma.Binding to retinoblastoma pocket domain does not alter the inter-domain flexibility of the J domain of SV40 large T antigenThe Hsp40 molecular chaperone Ydj1p, along with the protein kinase C pathway, affects cell-wall integrity in the yeast Saccharomyces cerevisiae.Enterocyte proliferation and intestinal hyperplasia induced by simian virus 40 T antigen require a functional J domainA screen for modulators of large T antigen's ATPase activity uncovers novel inhibitors of Simian Virus 40 and BK virus replication.Intestinal hyperplasia induced by simian virus 40 large tumor antigen requires E2F2.Cul7/p185/p193 binding to simian virus 40 large T antigen has a role in cellular transformation.Simian virus 40 T antigens and J domains: analysis of Hsp40 cochaperone functions in Escherichia coli.Merkel cell polyomavirus T antigens promote cell proliferation and inflammatory cytokine gene expressionThe conserved core enzymatic activities and the distinct dynamics of polyomavirus large T antigensPP2A-dependent disruption of centrosome replication and cytoskeleton organization in Drosophila by SV40 small tumor antigenReconstructing signal transduction pathways: challenges and opportunities.Association of simian virus 40 vp1 with 70-kilodalton heat shock proteins and viral tumor antigens.Regulation of the retinoblastoma proteins by the human herpesviruses.Simian virus 40 T-antigen-mediated gene regulation in enterocytes is controlled primarily by the Rb-E2F pathwayInhibition of Simian Virus 40 replication by targeting the molecular chaperone function and ATPase activity of T antigen.T antigen transgenic mouse modelsUnderstanding the targeting of the RB family proteins by viral oncoproteins to defeat their oncogenic machinery.Targeting EphA2 impairs cell cycle progression and growth of basal-like/triple-negative breast cancers.Human polyoma JC virus minor capsid proteins, VP2 and VP3, enhance large T antigen binding to the origin of viral DNA replication: evidence for their involvement in regulation of the viral DNA replication.J domain independent functions of J proteins.Kaposi's sarcoma-associated herpesvirus lana2 protein interacts with the pocket proteins and inhibits their sumoylation.ATP-dependent simian virus 40 T-antigen-Hsc70 complex formation.Inactivation of the retinoblastoma protein family can bypass the HCF-1 defect in tsBN67 cell proliferation and cytokinesis.
P2860
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P2860
The molecular chaperone activity of simian virus 40 large T antigen is required to disrupt Rb-E2F family complexes by an ATP-dependent mechanism.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年学术文章
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2000年学术文章
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2000年学术文章
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2000年学术文章
@zh-my
2000年学术文章
@zh-sg
2000年學術文章
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2000年學術文章
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name
The molecular chaperone activi ...... by an ATP-dependent mechanism.
@en
The molecular chaperone activi ...... by an ATP-dependent mechanism.
@nl
type
label
The molecular chaperone activi ...... by an ATP-dependent mechanism.
@en
The molecular chaperone activi ...... by an ATP-dependent mechanism.
@nl
prefLabel
The molecular chaperone activi ...... by an ATP-dependent mechanism.
@en
The molecular chaperone activi ...... by an ATP-dependent mechanism.
@nl
P2093
P2860
P1476
The molecular chaperone activi ...... by an ATP-dependent mechanism.
@en
P2093
C S Sullivan
P Cantalupo
P2860
P304
P356
10.1128/MCB.20.17.6233-6243.2000
P407
P577
2000-09-01T00:00:00Z