Substitutions in the glycoprotein (GP) of the Candid#1 vaccine strain of Junin virus increase dependence on human transferrin receptor 1 for entry and destabilize the metastable conformation of GP - Wikidata - wikimedia - TriplyDB

Substitutions in the glycoprotein (GP) of the Candid#1 vaccine strain of Junin virus increase dependence on human transferrin receptor 1 for entry and destabilize the metastable conformation of GP

Substitutions in the glycoprotein (GP) of the Candid#1 vaccine strain of Junin virus increase dependence on human transferrin receptor 1 for entry and destabilize the metastable conformation of GP

http://www.wikidata.org/entity/Q39462623

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Advanced vaccine candidates for Lassa fever Junín virus pathogenesis and virus replication The Ectodomain of Glycoprotein from the Candid#1 Vaccine Strain of Junin Virus Rendered Machupo Virus Partially Attenuated in Mice Lacking IFN-αβ/γ Receptor Biochemical reconstitution of hemorrhagic-fever arenavirus envelope glycoprotein-mediated membrane fusion Identification and Characterization of a Novel Broad-Spectrum Virus Entry Inhibitor.Potent inhibition of Junín virus infection by interferon in murine cells.The curious case of arenavirus entry, and its inhibition.A systems biology starter kit for arenaviruses.Development of live-attenuated arenavirus vaccines based on codon deoptimization The glycoprotein precursor gene of Junin virus determines the virulence of the Romero strain and the attenuation of the Candid #1 strain in a representative animal model of Argentine hemorrhagic fever.Novel Arenavirus Entry Inhibitors Discovered by Using a Minigenome Rescue System for High-Throughput Drug Screening.Machupo Virus Expressing GPC of the Candid#1 Vaccine Strain of Junin Virus Is Highly Attenuated and Immunogenic.Evaluation of Lassa virus vaccine immunogenicity in a CBA/J-ML29 mouse model Myristoylation of the Arenavirus Envelope Glycoprotein Stable Signal Peptide Is Critical for Membrane Fusion but Dispensable for Virion Morphogenesis Development of live-attenuated arenavirus vaccines based on codon deoptimization of the viral glycoprotein.Targeting virulence mechanisms for the prevention and therapy of arenaviral hemorrhagic fever.Human and host species transferrin receptor 1 use by North American arenaviruses.Human hemorrhagic Fever causing arenaviruses: molecular mechanisms contributing to virus virulence and disease pathogenesis.Absence of an N-Linked Glycosylation Motif in the Glycoprotein of the Live-Attenuated Argentine Hemorrhagic Fever Vaccine, Candid #1, Results in Its Improper Processing, and Reduced Surface Expression.Novel drug discovery approaches for treating arenavirus infections.Structure-function relationship of the mammarenavirus envelope glycoprotein.Arenavirus Genome Rearrangement for the Development of Live Attenuated Vaccines.A substitution in the transmembrane region of the glycoprotein leads to an unstable attenuation of Machupo virus.Epistastic interactions within the Junín virus envelope glycoprotein complex provide an evolutionary barrier to reversion in the live-attenuated Candid#1 vaccine.Vaccine-elicited receptor-binding site antibodies neutralize two New World hemorrhagic fever arenaviruses.Neutralization of Junín virus by single domain antibodies targeted against the nucleoprotein The S Genome Segment Is Sufficient to Maintain Pathogenicity in Intra-Clade Lassa Virus Reassortants in a Guinea Pig Model

P2860

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P2860

Substitutions in the glycoprotein (GP) of the Candid#1 vaccine strain of Junin virus increase dependence on human transferrin receptor 1 for entry and destabilize the metastable conformation of GP

http://www.wikidata.org/entity/Q39462623

description

2011 nî lūn-bûn

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2011年の論文

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2011年論文

@yue

2011年論文

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2011年論文

@zh-hk

2011年論文

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2011年論文

@zh-tw

2011年论文

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2011年论文

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2011年论文

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name

Substitutions in the glycoprot ...... metastable conformation of GP

@en

Substitutions in the glycoprotein

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type

label

Substitutions in the glycoprot ...... metastable conformation of GP

@en

Substitutions in the glycoprotein

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prefLabel

Substitutions in the glycoprot ...... metastable conformation of GP

@en

Substitutions in the glycoprotein

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P1433

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P2860

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P1433

Journal of Virology

P1476

Substitutions in the glycoprot ...... metastable conformation of GP

@en

P2093

Alex U Cox

http://www.w3.org/2001/XMLSchema#string

Colin M Exline

http://www.w3.org/2001/XMLSchema#string

Jessica Y Rathbun

http://www.w3.org/2001/XMLSchema#string

Jill E Oldenburg

http://www.w3.org/2001/XMLSchema#string

Magali E Droniou-Bonzom

http://www.w3.org/2001/XMLSchema#string

Paula M Cannon

http://www.w3.org/2001/XMLSchema#string

Therese Reignier

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P2860

Tight control of gene expression in mammalian cells by tetracycline-responsive promoters

Differences in tropism and pH dependence for glycoproteins from the Clade B1 arenaviruses: Implications for receptor usage and pathogenicity

Unusual Molecular Architecture of the Machupo Virus Attachment Glycoprotein

Structural basis for receptor recognition by New World hemorrhagic fever arenaviruses

The structural biology of type I viral membrane fusion

Identification of alpha-dystroglycan as a receptor for lymphocytic choriomeningitis virus and Lassa fever virus

Detection of replication-competent and pseudotyped human immunodeficiency virus with a sensitive cell line on the basis of activation of an integrated beta-galactosidase gene

Mechanisms of viral membrane fusion and its inhibition

Arenaviruses: protein structure and function.

Refolding of a paramyxovirus F protein from prefusion to postfusion conformations observed by liposome binding and electron microscopy.

P304

13457-13462

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scholarly article

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10.1128/JVI.05616-11

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P433

24

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85

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2011-10-05T00:00:00Z

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51696697

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21976641

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3233171

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