A Fragment-Based Approach for the Computational Prediction of the Nonspecific Binding of Drugs to Hepatic Microsomes.

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A Fragment-Based Approach for the Computational Prediction of the Nonspecific Binding of Drugs to Hepatic Microsomes.

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2016 nî lūn-bûn

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2016年の論文

@ja

2016年論文

@yue

2016年論文

@zh-hant

2016年論文

@zh-hk

2016年論文

@zh-mo

2016年論文

@zh-tw

2016年论文

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2016年论文

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2016年论文

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name

A Fragment-Based Approach for ...... f Drugs to Hepatic Microsomes.

@en

A Fragment-Based Approach for ...... f Drugs to Hepatic Microsomes.

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type

Item

label

A Fragment-Based Approach for ...... f Drugs to Hepatic Microsomes.

@en

A Fragment-Based Approach for ...... f Drugs to Hepatic Microsomes.

@nl

prefLabel

A Fragment-Based Approach for ...... f Drugs to Hepatic Microsomes.

@en

A Fragment-Based Approach for ...... f Drugs to Hepatic Microsomes.

@nl

P1476

A Fragment-Based Approach for ...... of Drugs to Hepatic Microsomes

@en

P2093

John O Miners

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P2860

Simulation and prediction of in vivo drug metabolism in human populations from in vitro data

Impact of nonspecific binding to microsomes and phospholipid on the inhibition of cytochrome P4502D6: implications for relating in vitro inhibition data to in vivo drug interactions.

Hologram QSAR model for the prediction of human oral bioavailability.

Hepatocellular binding of drugs: correction for unbound fraction in hepatocyte incubations using microsomal binding or drug lipophilicity data.

Nonspecific binding of drugs to human liver microsomes

In vitro-in vivo correlation for drugs and other compounds eliminated by glucuronidation in humans: pitfalls and promises.

The impact of in vitro binding on in vitro-in vivo extrapolations, projections of metabolic clearance and clinical drug-drug interactions.

Utility of in vitro drug metabolism data in predicting in vivo metabolic clearance.

Commentary: nonspecific protein binding versus membrane partitioning: it is not just semantics.

Inhibition of Human UDP-Glucuronosyltransferase Enzymes by Canagliflozin and Dapagliflozin: Implications for Drug-Drug Interactions.

P304

1794-1798

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P31

scholarly article

P356

10.1124/DMD.116.071852

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P433

http://www.w3.org/2001/XMLSchema#string

P478

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P50

Pramod C. Nair

Ross A. McKinnon

P577

2016-08-19T00:00:00Z

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P698

27543205

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