Development of indole compounds as small molecule fusion inhibitors targeting HIV-1 glycoprotein-41.
about
Regioselective Glucuronidation of Diosmetin and Chrysoeriol by the Interplay of Glucuronidation and Transport in UGT1A9-Overexpressing HeLa CellsIdentification of fragments targeting an alternative pocket on HIV-1 gp41 by NMR screening and similarity searching.Design and characterization of swapped-domain constructs of HIV-1 glycoprotein-41 as receptors for drug discovery.Discovery of HIV fusion inhibitors targeting gp41 using a comprehensive α-helix mimetic library.Inhibition of HIV Entry by Targeting the Envelope Transmembrane Subunit gp41.Enhanced potency of bivalent small molecule gp41 inhibitors.Footprint-based identification of viral entry inhibitors targeting HIVgp41.Swapped-domain constructs of the glycoprotein-41 ectodomain are potent inhibitors of HIV infectionA suite of modular fluorescence assays interrogate the human immunodeficiency virus glycoprotein-41 coiled coil and assist in determining binding mechanism of low molecular weight fusion inhibitors.Development of Small-molecule HIV Entry Inhibitors Specifically Targeting gp120 or gp41Approaches for identification of HIV-1 entry inhibitors targeting gp41 pocketComputer-Aided Approaches for Targeting HIVgp41.Molecular dynamics modeling the synthetic and biological polymers interactions pre-studied via docking: anchors modified polyanions interference with the HIV-1 fusion mediatorEvaluation of ligand-based NMR screening methods to characterize small molecule binding to HIV-1 glycoprotein-41.Synthesis, Biological Evaluation and Molecular Docking Studies of Novel 4-Arylpyridin-1(4H)-yl) benzoic acid Derivatives as Anti-HIV-1 Agents.Site-selective Suzuki-Miyaura coupling of heteroaryl halides - understanding the trends for pharmaceutically important classes.Structure-activity relationship studies of indole-based compounds as small molecule HIV-1 fusion inhibitors targeting glycoprotein 41.Artificial peptides conjugated with cholesterol and pocket-specific small molecules potently inhibit infection by laboratory-adapted and primary HIV-1 isolates and enfuvirtide-resistant HIV-1 strains.Anti-HIV-1 Activity Prediction of Novel Gp41 Inhibitors Using Structure-Based Virtual Screening and Molecular Dynamics Simulation.Scope of the two-step, one-pot palladium-catalyzed borylation/Suzuki cross-coupling reaction utilizing bis-boronic acidAn effective conjugation strategy for designing short peptide-based HIV-1 fusion inhibitors.Concise synthesis and anti-HIV activity of pyrimido[1,2-c][1,3]benzothiazin-6-imines and related tricyclic heterocycles.A novel view of modelling interactions between synthetic and biological polymers via docking.A General Nickel-Catalyzed Method for C-H Bond Alkynylation of Heteroarenes Through Chelation Assistance.A Novel gp41-Binding Adnectin with Potent Anti-HIV Activity Is Highly Synergistic when Linked to a CD4-Binding Adnectin.
P2860
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P2860
Development of indole compounds as small molecule fusion inhibitors targeting HIV-1 glycoprotein-41.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Development of indole compound ...... rgeting HIV-1 glycoprotein-41.
@en
Development of indole compound ...... rgeting HIV-1 glycoprotein-41.
@nl
type
label
Development of indole compound ...... rgeting HIV-1 glycoprotein-41.
@en
Development of indole compound ...... rgeting HIV-1 glycoprotein-41.
@nl
prefLabel
Development of indole compound ...... rgeting HIV-1 glycoprotein-41.
@en
Development of indole compound ...... rgeting HIV-1 glycoprotein-41.
@nl
P2093
P2860
P356
P1476
Development of indole compound ...... rgeting HIV-1 glycoprotein-41.
@en
P2093
Beth Snyder
Guangyan Zhou
Harmeet Kaur
Miriam Gochin
Roger G Ptak
P2860
P304
P356
10.1021/JM200791Z
P407
P577
2011-10-03T00:00:00Z