NBS1 recruits RAD18 via a RAD6-like domain and regulates Pol η-dependent translesion DNA synthesis.
about
Transcriptional repressor ZBTB1 promotes chromatin remodeling and translesion DNA synthesisThe Regulation of DNA Damage Tolerance by Ubiquitin and Ubiquitin-Like ModifiersFunctional Role of NBS1 in Radiation Damage Response and Translesion DNA SynthesisRNF20-SNF2H Pathway of Chromatin Relaxation in DNA Double-Strand Break RepairSIVA1 directs the E3 ubiquitin ligase RAD18 for PCNA monoubiquitination.Parkin regulates translesion DNA synthesis in response to UV radiationNijmegen breakage syndrome fibroblasts expressing the C-terminal truncated NBN(p70) protein undergo p38/MK2-dependent premature senescence.The Mre11-Rad50-Xrs2 complex is required for yeast DNA postreplication repairRelevance of simultaneous mono-ubiquitinations of multiple units of PCNA homo-trimers in DNA damage tolerance.c-Jun N-terminal kinase-mediated Rad18 phosphorylation facilitates Polη recruitment to stalled replication forksNBS1 and multiple regulations of DNA damage response.PCNA-Dependent Cleavage and Degradation of SDE2 Regulates Response to Replication StressCell cycle stage-specific roles of Rad18 in tolerance and repair of oxidative DNA damageTRF2-RAP1 is required to protect telomeres from engaging in homologous recombination-mediated deletions and fusions.A non-catalytic role of DNA polymerase η in recruiting Rad18 and promoting PCNA monoubiquitination at stalled replication forksA neomorphic cancer cell-specific role of MAGE-A4 in trans-lesion synthesis.BRCA1 promotes the ubiquitination of PCNA and recruitment of translesion polymerases in response to replication blockade.Mismatch repair protein MSH2 regulates translesion DNA synthesis following exposure of cells to UV radiation.Mechanisms of Post-Replication DNA RepairAssociation between the NBS1 Glu185Gln polymorphism and lung cancer risk: a systemic review and meta-analysis.Regulation of Rad6/Rad18 Activity During DNA Damage Tolerance.Mutations in the FHA-domain of ectopically expressed NBS1 lead to radiosensitization and to no increase in somatic mutation rates via a partial suppression of homologous recombination.NBS1 is regulated by two kind of mechanisms: ATM-dependent complex formation with MRE11 and RAD50, and cell cycle-dependent degradation of protein.DNA repair factor RAD18 and DNA polymerase Polκ confer tolerance of oncogenic DNA replication stress.
P2860
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P2860
NBS1 recruits RAD18 via a RAD6-like domain and regulates Pol η-dependent translesion DNA synthesis.
description
2011 nî lūn-bûn
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2011年の論文
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2011年学术文章
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2011年学术文章
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2011年学术文章
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2011年学术文章
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2011年学术文章
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name
NBS1 recruits RAD18 via a RAD6 ...... ent translesion DNA synthesis.
@en
NBS1 recruits RAD18 via a RAD6 ...... ent translesion DNA synthesis.
@nl
type
label
NBS1 recruits RAD18 via a RAD6 ...... ent translesion DNA synthesis.
@en
NBS1 recruits RAD18 via a RAD6 ...... ent translesion DNA synthesis.
@nl
prefLabel
NBS1 recruits RAD18 via a RAD6 ...... ent translesion DNA synthesis.
@en
NBS1 recruits RAD18 via a RAD6 ...... ent translesion DNA synthesis.
@nl
P2093
P1433
P1476
NBS1 recruits RAD18 via a RAD6 ...... dent translesion DNA synthesis
@en
P2093
Akihiro Kato
Chikahide Masutani
Corry M Weemaes
Fumio Hanaoka
Hiromi Yanagihara
Hiroshi Tauchi
Jun Takezawa
Junya Kobayashi
Kaoru Sugasawa
Kenshi Komatsu
P304
P356
10.1016/J.MOLCEL.2011.07.026
P577
2011-09-01T00:00:00Z