about
In-vivo efficacy of compliant 3D nano-composite in critical-size bone defect repair: a six month preclinical study in rabbitTotal water, phosphorus relaxation and inter-atomic organic to inorganic interface are new determinants of trabecular bone integrityCross-correlative 3D micro-structural investigation of human bone processed into bone allografts.Agonists of the retinoic acid- and retinoid X-receptors inhibit hepatocyte growth factor secretion and expression in U87 human astrocytoma cells.Calcium-sensing receptor in the brain.A high-throughput drug screen targeted to the 5'untranslated region of Alzheimer amyloid precursor protein mRNA.Cellular "sensing" of extracellular calcium (Ca(2+)(o)): emerging roles in regulating diverse physiological functions.The calcium-sensing receptor in human disease.Estrogen deficiency induces the differentiation of IL-17 secreting Th17 cells: a new candidate in the pathogenesis of osteoporosis.Expression of extracellular calcium-sensing receptor by human lens epithelial cells.Pathophysiological Mechanism of Bone Loss in Type 2 Diabetes Involves Inverse Regulation of Osteoblast Function by PGC-1α and Skeletal Muscle Atrogenes: AdipoR1 as a Potential Target for Reversing Diabetes-Induced Osteopenia.Proteomic discovery of MNT as a novel interacting partner of E3 ubiquitin ligase E6AP and a key mediator of myeloid differentiation.A novel therapeutic approach with Caviunin-based isoflavonoid that en routes bone marrow cells to bone formation via BMP2/Wnt-β-catenin signalingA naturally occurring naringenin derivative exerts potent bone anabolic effects by mimicking oestrogen action on osteoblastsAdipose-Derived Mesenchymal Stem Cells Prevent Systemic Bone Loss in Collagen-Induced ArthritisEffects of calcium-sensing receptor on the secretion of parathyroid hormone-related peptide and its impact on humoral hypercalcemia of malignancy.Role of calcium-sensing receptor in mineral ion metabolism and inherited disorders of calcium-sensing.Greater Skeletal Gains in Ovary Intact Rats at Maturity Are Achieved by Supplementing a Standardized Extract of Butea monosperma Stem Bark that Confers Better Bone Conserving Effect following Ovariectomy and Concurrent Treatment WithdrawalParathyroid hormone ablation alters erythrocyte parameters that are rescued by calcium-sensing receptor gene deletion.Recent updates on the calcium-sensing receptor as a drug target.Anabolics in osteoporosis: the emerging therapeutic tool.Diverse roles of extracellular calcium-sensing receptor in the central nervous system.Signaling through the extracellular calcium-sensing receptor (CaSR).E6AP inhibits G-CSFR turnover and functions by promoting its ubiquitin-dependent proteasome degradation.Characterization of BMP signaling dependent osteogenesis using a BMP depletable avianized bone marrow stromal cell line (TVA-BMSC).Pharmacological inhibition of cathepsin K: A promising novel approach for postmenopausal osteoporosis therapy.Quercetin-6-C-β-D-glucopyranoside, natural analog of quercetin exhibits anti-prostate cancer activity by inhibiting Akt-mTOR pathway via aryl hydrocarbon receptor.Prunetin signals via G-protein-coupled receptor, GPR30(GPER1): Stimulation of adenylyl cyclase and cAMP-mediated activation of MAPK signaling induces Runx2 expression in osteoblasts to promote bone regeneration.Thioaryl naphthylmethanone oxime ether analogs as novel anticancer agents.Amino acids derived benzoxazepines: design, synthesis and antitumor activity.Design and synthesis of 1,3-biarylsulfanyl derivatives as new anti-breast cancer agents.Specific targeting of insulin-like growth factor 1 receptor signaling in human estrogen dependent breast cancer cell by a novel tyrosine-based benzoxazepine derivative.A novel flavonoid isolated from the steam-bark of Ulmus wallichiana planchon stimulates osteoblast function and inhibits osteoclast and adipocyte differentiation.Anti-tumor activity of a new series of benzoxazepine derivatives in breast cancer.Kaempferol and quercetin stimulate granulocyte-macrophage colony-stimulating factor secretion in human prostate cancer cells.Skp2 inhibits osteogenesis by promoting ubiquitin-proteasome degradation of Runx2.Cell growth inhibitory action of an unusual labdane diterpene, 13-epi-sclareol in breast and uterine cancers in vitro.The calcium-sensing receptor (CaR) is involved in strontium ranelate-induced osteoblast proliferation.The calcium sensing receptor is directly involved in both osteoclast differentiation and apoptosis.Attenuation of osteoclastogenesis and osteoclast function by apigenin.
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