Paraptosis accompanied by autophagy and apoptosis was induced by celastrol, a natural compound with influence on proteasome, ER stress and Hsp90. - Wikidata - wikimedia - TriplyDB

Paraptosis accompanied by autophagy and apoptosis was induced by celastrol, a natural compound with influence on proteasome, ER stress and Hsp90.

Paraptosis accompanied by autophagy and apoptosis was induced by celastrol, a natural compound with influence on proteasome, ER stress and Hsp90.

http://www.wikidata.org/entity/Q39484780

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The Natural Occurring Compounds Targeting Endoplasmic Reticulum Stress Cytoplasmic vacuolization in cell death and survival Broad targeting of angiogenesis for cancer prevention and therapy Review of tumor dormancy therapy using traditional oriental herbal medicine Upregulating Noxa by ER stress, celastrol exerts synergistic anti-cancer activity in combination with ABT-737 in human hepatocellular carcinoma cells mTOR inhibition by everolimus in childhood acute lymphoblastic leukemia induces caspase-independent cell death Celastrol inhibits lung infiltration in differential syndrome animal models by reducing TNF-α and ICAM-1 levels while preserving differentiation in ATRA-induced acute promyelocytic leukemia cells SNIPER(TACC3) induces cytoplasmic vacuolization and sensitizes cancer cells to Bortezomib.Xanthohumol induces paraptosis of leukemia cells through p38 mitogen activated protein kinase signaling pathway.Celastrol prevents cadmium-induced neuronal cell death via targeting JNK and PTEN-Akt/mTOR network.Release of Ca2+ from the endoplasmic reticulum and its subsequent influx into mitochondria trigger celastrol-induced paraptosis in cancer cells.ER stress-mediated apoptosis induced by celastrol in cancer cells and important role of glycogen synthase kinase-3β in the signal network.Lipid droplet binding thalidomide analogs activate endoplasmic reticulum stress and suppress hepatocellular carcinoma in a chemically induced transgenic mouse model.Activation of autophagy and paraptosis in retinal ganglion cells after retinal ischemia and reperfusion injury in rats.The quinone methide aurin is a heat shock response inducer that causes proteotoxic stress and Noxa-dependent apoptosis in malignant melanoma cells.Celastrol inhibits gastric cancer growth by induction of apoptosis and autophagy.8-p-Hdroxybenzoyl Tovarol Induces Paraptosis Like Cell Death and Protective Autophagy in Human Cervical Cancer HeLa Cells.Development of EBV-encoded small RNA targeted PCR to classify EBV positive diffuse large B-cell lymphoma (DLBCL) of the elderly.Microarray-based gene expression profiling reveals the mediators and pathways involved in the anti-arthritic activity of Celastrus-derived Celastrol.Everolimus downregulates estrogen receptor and induces autophagy in aromatase inhibitor-resistant breast cancer cells.Celastrol ameliorates Cd-induced neuronal apoptosis by targeting NOX2-derived ROS-dependent PP5-JNK signaling pathway.Celastrol induces apoptosis and autophagy via the ROS/JNK signaling pathway in human osteosarcoma cells: an in vitro and in vivo study.Marchantin M: a novel inhibitor of proteasome induces autophagic cell death in prostate cancer cells.125I Seeds Radiation Induces Paraptosis-Like Cell Death via PI3K/AKT Signaling Pathway in HCT116 Cells Prostate cancer and the unfolded protein response.Stronger proteasomal inhibition and higher CHOP induction are responsible for more effective induction of paraptosis by dimethoxycurcumin than curcumin.Therapeutic targeting of cancer cell cycle using proteasome inhibitors Synthesis and pharmacology of proteasome inhibitors.Cross-talk between apoptosis and autophagy in lung epithelial cell death.Dinuclear [{(p-cym)RuCl}2(μ-phpy)](PF6)2 and heterodinuclear [(ppy)2Ir(μ-phpy)Ru(p-cym)Cl](PF6)2 complexes: synthesis, structure and anticancer activity.Celastrol induces unfolded protein response-dependent cell death in head and neck cancer.Selenium induces a multi-targeted cell death process in addition to ROS formation.A novel copper(I) complex induces ER-stress-mediated apoptosis and sensitizes B-acute lymphoblastic leukemia cells to chemotherapeutic agents.Celastrol targets proteostasis and acts synergistically with a heat-shock protein 90 inhibitor to kill human glioblastoma cells.Natural products as modulator of autophagy with potential clinical prospects.Celastrol induced DNA damage, cell cycle arrest, and apoptosis in human rheumatoid fibroblast-like synovial cells.The extent of neurodegeneration and neuroprotection in two chemical in vitro models related to Parkinson's disease is critically dependent on cell culture conditions.Natural Compounds As Modulators of Non-apoptotic Cell Death in Cancer Cells.Compounds From Celastraceae Targeting Cancer Pathways and Their Potential Application in Head and Neck Squamous Cell Carcinoma: A Review.Natural Compounds from Herbs that can Potentially Execute as Autophagy Inducers for Cancer Therapy.

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P2860

Paraptosis accompanied by autophagy and apoptosis was induced by celastrol, a natural compound with influence on proteasome, ER stress and Hsp90.

http://www.wikidata.org/entity/Q39484780

description

2012 nî lūn-bûn

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2012年の論文

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年學術文章

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2012年學術文章

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2012年學術文章

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name

Paraptosis accompanied by auto ...... oteasome, ER stress and Hsp90.

@en

Paraptosis accompanied by auto ...... oteasome, ER stress and Hsp90.

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type

label

Paraptosis accompanied by auto ...... oteasome, ER stress and Hsp90.

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Paraptosis accompanied by auto ...... oteasome, ER stress and Hsp90.

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prefLabel

Paraptosis accompanied by auto ...... oteasome, ER stress and Hsp90.

@en

Paraptosis accompanied by auto ...... oteasome, ER stress and Hsp90.

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P356

P1433

Journal of Cellular Physiology

P1476

Paraptosis accompanied by auto ...... oteasome, ER stress and Hsp90.

@en

P2093

Bao-Hong Jiang

http://www.w3.org/2001/XMLSchema#string

De-An Guo

http://www.w3.org/2001/XMLSchema#string

Li-Xing Feng

http://www.w3.org/2001/XMLSchema#string

Min Yang

http://www.w3.org/2001/XMLSchema#string

Qing-Xi Yue

http://www.w3.org/2001/XMLSchema#string

Shu-Hong Guan

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Wan-Ying Wu

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Wen-Bo Wang

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Xuan Liu

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P2860

The thioxotriazole copper(II) complex A0 induces endoplasmic reticulum stress and paraptotic death in human cancer cells

Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009

An alternative, nonapoptotic form of programmed cell death

Proteomics characterization of the cytotoxicity mechanism of ganoderic acid D and computer-automated estimation of the possible drug target network.

Taxol induces caspase-independent cytoplasmic vacuolization and cell death through endoplasmic reticulum (ER) swelling in ASTC-a-1 cells.

Dual role of 3-methyladenine in modulation of autophagy via different temporal patterns of inhibition on class I and III phosphoinositide 3-kinase

Celastrol, a potent antioxidant and anti-inflammatory drug, as a possible treatment for Alzheimer's disease.

Identification of new modulators and protein alterations in non-apoptotic programmed cell death.

Paraptosis: mediation by MAP kinases and inhibition by AIP-1/Alix.

Celastrol, a triterpene extracted from the Chinese "Thunder of God Vine," is a potent proteasome inhibitor and suppresses human prostate cancer growth in nude mice.

P304

2196-2206

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P356

10.1002/JCP.22956

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5

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P478

227

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2012-05-01T00:00:00Z

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P698

21866552

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P921

apoptotic process