The heat shock protein 90 inhibitor IPI-504 induces KIT degradation, tumor shrinkage, and cell proliferation arrest in xenograft models of gastrointestinal stromal tumors.

The heat shock protein 90 inhibitor IPI-504 induces KIT degradation, tumor shrinkage, and cell proliferation arrest in xenograft models of gastrointestinal stromal tumors.

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http://www.wikidata.org/entity/Q39493276
Assessing tumor vascularization as a potential biomarker of imatinib resistance in gastrointestinal stromal tumors by dynamic contrast-enhanced magnetic resonance imaging.Characterization and assessment of the sensitivity and resistance of a newly established human gastrointestinal stromal tumour xenograft model to treatment with tyrosine kinase inhibitors.Drug repurposing identifies a synergistic combination therapy with imatinib mesylate for gastrointestinal stromal tumor.MTOR inhibition enhances NVP-AUY922-induced autophagy-mediated KIT degradation and cytotoxicity in imatinib-resistant gastrointestinal stromal tumors.A phase I study of the HSP90 inhibitor retaspimycin hydrochloride (IPI-504) in patients with gastrointestinal stromal tumors or soft-tissue sarcomas.Therapeutic Efficacy Assessment of CK6, a Monoclonal KIT Antibody, in a Panel of Gastrointestinal Stromal Tumor Xenograft Models.Autophagy is involved in endogenous and NVP-AUY922-induced KIT degradation in gastrointestinal stromal tumors.Update on imatinib for gastrointestinal stromal tumors: duration of treatment.Reduced Contractility and Motility of Prostatic Cancer-Associated Fibroblasts after Inhibition of Heat Shock Protein 90Therapeutic targeting of c-KIT in cancer.Discovery and development of heat shock protein 90 inhibitors as anticancer agents: a review of patented potent geldanamycin derivatives.GIST treatment options after tyrosine kinase inhibitors.Natural Product Inspired N-Terminal Hsp90 Inhibitors: From Bench to Bedside?The HSP90 inhibitor, AT13387, is effective against imatinib-sensitive and -resistant gastrointestinal stromal tumor models.Novel Insights into the Treatment of Imatinib-Resistant Gastrointestinal Stromal Tumors.A Phase 2 Study of the Hsp90 Inhibitor AUY922 as Treatment for Patients with Refractory Gastrointestinal Stromal Tumors.New targets and therapies for gastrointestinal stromal tumors.
P2860

The heat shock protein 90 inhibitor IPI-504 induces KIT degradation, tumor shrinkage, and cell proliferation arrest in xenograft models of gastrointestinal stromal tumors.

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http://www.wikidata.org/entity/Q39493276
description
2011 nî lūn-bûn
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2011年の論文
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2011年学术文章
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2011年学术文章
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2011年学术文章
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2011年学术文章
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2011年学术文章
@zh-sg
2011年學術文章
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2011年學術文章
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2011年學術文章
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name
The heat shock protein 90 inhi ...... strointestinal stromal tumors.
@en
The heat shock protein 90 inhi ...... strointestinal stromal tumors.
@nl
type
label
The heat shock protein 90 inhi ...... strointestinal stromal tumors.
@en
The heat shock protein 90 inhi ...... strointestinal stromal tumors.
@nl
prefLabel
The heat shock protein 90 inhi ...... strointestinal stromal tumors.
@en
The heat shock protein 90 inhi ...... strointestinal stromal tumors.
@nl
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The heat shock protein 90 inhi ...... strointestinal stromal tumors.
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P2093
P304
P31
P356
10.1158/1535-7163.MCT-11-0148
P433
P478
P50
P577
P698
P921