Gene targeting in Penicillium chrysogenum: disruption of the lys2 gene leads to penicillin overproduction.
about
Identification of the viridicatumtoxin and griseofulvin gene clusters from Penicillium aethiopicumThe fungal α-aminoadipate pathway for lysine biosynthesis requires two enzymes of the aconitase family for the isomerization of homocitrate to homoisocitrateAmplification and disruption of the phenylacetyl-CoA ligase gene of Penicillium chrysogenum encoding an aryl-capping enzyme that supplies phenylacetic acid to the isopenicillin N-acyltransferaseTranscriptome analysis of the two unrelated fungal β-lactam producers Acremonium chrysogenum and Penicillium chrysogenum: Velvet-regulated genes are major targets during conventional strain improvement programs.Uptake of the beta-lactam precursor alpha-aminoadipic acid in Penicillium chrysogenum is mediated by the acidic and the general amino acid permease.Bidirectional-genetics platform, a dual-purpose mutagenesis strategy for filamentous fungi.xylP promoter-based expression system and its use for antisense downregulation of the Penicillium chrysogenum nitrogen regulator NRE.Targeted inactivation of the mecB gene, encoding cystathionine-gamma-lyase, shows that the reverse transsulfuration pathway is required for high-level cephalosporin biosynthesis in Acremonium chrysogenum C10 but not for methionine induction of the cConversion of pipecolic acid into lysine in Penicillium chrysogenum requires pipecolate oxidase and saccharopine reductase: characterization of the lys7 gene encoding saccharopine reductase.Silencing of the aspergillopepsin B (pepB) gene of Aspergillus awamori by antisense RNA expression or protease removal by gene disruption results in a large increase in thaumatin production.Controlled expression of an rpoS antisense RNA can inhibit RpoS function in Escherichia coli.Inactivation of the lys7 gene, encoding saccharopine reductase in Penicillium chrysogenum, leads to accumulation of the secondary metabolite precursors piperideine-6-carboxylic acid and pipecolic acid from alpha-aminoadipic acid.
P2860
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P2860
Gene targeting in Penicillium chrysogenum: disruption of the lys2 gene leads to penicillin overproduction.
description
1999 nî lūn-bûn
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1999年の論文
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1999年学术文章
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1999年学术文章
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name
Gene targeting in Penicillium ...... to penicillin overproduction.
@en
Gene targeting in Penicillium ...... to penicillin overproduction.
@nl
type
label
Gene targeting in Penicillium ...... to penicillin overproduction.
@en
Gene targeting in Penicillium ...... to penicillin overproduction.
@nl
prefLabel
Gene targeting in Penicillium ...... to penicillin overproduction.
@en
Gene targeting in Penicillium ...... to penicillin overproduction.
@nl
P2093
P2860
P1476
Gene targeting in Penicillium ...... s to penicillin overproduction
@en
P2093
J F Martín
M J Hijarrubia
O Bañuelos
S Gutiérrez
P2860
P304
P407
P577
1999-02-01T00:00:00Z