Discovery and characterization of 2-aminobenzimidazole derivatives as selective NOD1 inhibitors. - Wikidata - wikimedia - TriplyDB

Discovery and characterization of 2-aminobenzimidazole derivatives as selective NOD1 inhibitors.

Discovery and characterization of 2-aminobenzimidazole derivatives as selective NOD1 inhibitors.

http://www.wikidata.org/entity/Q39498341

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Roles of NOD1 (NLRC1) and NOD2 (NLRC2) in innate immunity and inflammatory diseases RIP2 activity in inflammatory disease and implications for novel therapeutics Identification of selective small molecule inhibitors of the nucleotide-binding oligomerization domain 1 (NOD1) signaling pathway Identification of benzimidazole diamides as selective inhibitors of the nucleotide-binding oligomerization domain 2 (NOD2) signaling pathway TNFα and IL-1β are mediated by both TLR4 and Nod1 pathways in the cultured HAPI cells stimulated by LPS Therapeutic targeting of NOD1 receptors Identification of Inhibitors of NOD1-Induced Nuclear Factor-κB Activation.Human Toll-like receptor 8-selective agonistic activities in 1-alkyl-1H-benzimidazol-2-amines NOD1 and NOD2: signaling, host defense, and inflammatory disease.Bacterial peptidoglycan stimulates adipocyte lipolysis via NOD1.Functionalized Benzimidazole Scaffolds: Privileged Heterocycle for Drug Design in Therapeutic Medicine.Efficacy of the nucleotide-binding oligomerzation domain 1 inhibitor Nodinhibit-1 on corneal alkali burns in rats.Role of nucleotide-binding oligomerization domain 1 (NOD1) and its variants in human cytomegalovirus control in vitro and in vivo.Peptidoglycan as Nod1 ligand; fragment structures in the environment, chemical synthesis, and their innate immunostimulation.The versatile roles of CARDs in regulating apoptosis, inflammation, and NF-κB signaling.NOD1 receptor is up-regulated in diabetic human and murine myocardium.Expression, purification, and characterization of recombinant NOD1 (NLRC1): A NLR family member.Nucleotide-binding oligomerization domain 1 and gastrointestinal disorders.Anti-Inflammatory Effect of Columbianetin on Lipopolysaccharide-Stimulated Human Peripheral Blood Mononuclear Cells.Emerging Mechanisms of Innate Immunity and Their Translational Potential in Inflammatory Bowel Disease.Expression and in vitro assessment of tumorigenicity for NOD1 and NOD2 receptors in breast cancer cell lines.

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Discovery and characterization of 2-aminobenzimidazole derivatives as selective NOD1 inhibitors.

http://www.wikidata.org/entity/Q39498341

description

2011 nî lūn-bûn

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2011年学术文章

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2011年学术文章

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2011年学术文章

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2011年學術文章

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2011年學術文章

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2011年學術文章

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name

Discovery and characterization ...... as selective NOD1 inhibitors.

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Discovery and characterization ...... as selective NOD1 inhibitors.

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Discovery and characterization ...... as selective NOD1 inhibitors.

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Discovery and characterization ...... as selective NOD1 inhibitors.

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prefLabel

Discovery and characterization ...... as selective NOD1 inhibitors.

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Discovery and characterization ...... as selective NOD1 inhibitors.

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J.CHEMBIOL.2011.06.009

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Chemistry and Biology

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Discovery and characterization ...... as selective NOD1 inhibitors.

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Brock Brown

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Dayong Zhai

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Eduard Sergienko

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Gavin Magnuson

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Gregory P Roth

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John C Reed

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Nadav Askari

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Pasha M Khan

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Paul W Diaz

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Salvatore Albani

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P2860

Nod1, an Apaf-1-like activator of caspase-9 and nuclear factor-kappaB

The Nodosome: Nod1 and Nod2 control bacterial infections and inflammation

The NLR gene family: a standard nomenclature

A critical role of RICK/RIP2 polyubiquitination in Nod-induced NF-kappaB activation

SGT1 is essential for Nod1 activation

Human CARD4 protein is a novel CED-4/Apaf-1 cell death family member that activates NF-kappaB

Inflammatory caspases and inflammasomes: master switches of inflammation

Signalling pathways and molecular interactions of NOD1 and NOD2

CARD6 is a modulator of NF-kappa B activation by Nod1- and Cardiak-mediated pathways

An essential role for NOD1 in host recognition of bacterial peptidoglycan containing diaminopimelic acid

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825-832

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10.1016/J.CHEMBIOL.2011.06.009

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18

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