Podoplanin is regulated by AP-1 and promotes platelet aggregation and cell migration in osteosarcoma
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Podoplanin - a small glycoprotein with many facesTGF-β Signaling in Bone Remodeling and Osteosarcoma ProgressionPodoplanin: emerging functions in development, the immune system, and cancerTargeting a novel domain in podoplanin for inhibiting platelet-mediated tumor metastasisSyk and Src family kinases regulate C-type lectin receptor 2 (CLEC-2)-mediated clustering of podoplanin and platelet adhesion to lymphatic endothelial cells.Podoplanin enhances lung cancer cell growth in vivo by inducing platelet aggregationPlatelets promote osteosarcoma cell growth through activation of the platelet-derived growth factor receptor-Akt signaling axis.Activated platelets rescue apoptotic cells via paracrine activation of EGFR and DNA-dependent protein kinase.LpMab-12 Established by CasMab Technology Specifically Detects Sialylated O-Glycan on Thr52 of Platelet Aggregation-Stimulating Domain of Human Podoplanin.Phosphorylated mTOR expression correlates with podoplanin expression and high tumor grade in esophageal squamous cell carcinoma.Regulation of osteosarcoma cell lung metastasis by the c-Fos/AP-1 target FGFR1.The chimeric antibody chLpMab-7 targeting human podoplanin suppresses pulmonary metastasis via ADCC and CDC rather than via its neutralizing activity.The osteocyte: an endocrine cell ... and more.Podoplanin expression in cancer-associated fibroblasts enhances tumor progression of invasive ductal carcinoma of the pancreas.MicroRNA-199a-5p promotes tumour growth by dual-targeting PIAS3 and p27 in human osteosarcoma.Development and characterization of anti-glycopeptide monoclonal antibodies against human podoplanin, using glycan-deficient cell lines generated by CRISPR/Cas9 and TALEN.Podoplanin--a novel marker in oral carcinogenesis.Significance of MTA1 in the molecular characterization of osteosarcoma.Emerging roles of podoplanin in vascular development and homeostasis.Platelet-activating factor podoplanin: from discovery to drug developmentGenetic factors conferring metastasis in osteosarcoma.Characterization of monoclonal antibody LpMab-3 recognizing sialylated glycopeptide of podoplanin.Osteocytes serve as a progenitor cell of osteosarcoma.Ebp1 activates podoplanin expression and contributes to oral tumorigenesis.Antitumor activity of chLpMab-2, a human-mouse chimeric cancer-specific antihuman podoplanin antibody, via antibody-dependent cellular cytotoxicity.Podoplanin increases the migration of human fibroblasts and affects the endothelial cell network formation: A possible role for cancer-associated fibroblasts in breast cancer progression.Podoplanin is a novel myoepithelial cell marker in pleomorphic adenoma and other salivary gland tumors with myoepithelial differentiation.c-Fos mediates α1, 2-fucosyltransferase 1 and Lewis y expression in response to TGF-β1 in ovarian cancer.LpMab-23-recognizing cancer-type podoplanin is a novel predictor for a poor prognosis of early stage tongue cancer.Transforming Growth Factor-β Signaling Plays a Pivotal Role in the Interplay Between Osteosarcoma Cells and Their Microenvironment.A safety study of newly generated anti-podoplanin-neutralizing antibody in cynomolgus monkey ()
P2860
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P2860
Podoplanin is regulated by AP-1 and promotes platelet aggregation and cell migration in osteosarcoma
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年学术文章
@wuu
2011年学术文章
@zh-cn
2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
@yue
2011年學術文章
@zh
2011年學術文章
@zh-hant
name
Podoplanin is regulated by AP- ...... cell migration in osteosarcoma
@en
Podoplanin is regulated by AP- ...... ell migration in osteosarcoma.
@nl
type
label
Podoplanin is regulated by AP- ...... cell migration in osteosarcoma
@en
Podoplanin is regulated by AP- ...... ell migration in osteosarcoma.
@nl
prefLabel
Podoplanin is regulated by AP- ...... cell migration in osteosarcoma
@en
Podoplanin is regulated by AP- ...... ell migration in osteosarcoma.
@nl
P2093
P2860
P1476
Podoplanin is regulated by AP- ...... cell migration in osteosarcoma
@en
P2093
Agamemnon E Grigoriadis
Akiko Kunita
Atsushi Ohazama
Masashi Fukayama
Takeshi G Kashima
P2860
P304
P356
10.1016/J.AJPATH.2011.04.027
P407
P577
2011-06-12T00:00:00Z