Molecular and Dynamic Mechanism Underlying Drug Resistance in Genotype 3 Hepatitis C NS3/4A Protease.

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Applications of computer-aided approaches in the development of hepatitis C antiviral agents.Hepatitis C Virus NS3/4A Protease Inhibitors Incorporating Flexible P2 Quinoxalines Target Drug Resistant Viral Variants.Resistance to DAAs: When to Look and When It Matters.

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P2860

Molecular and Dynamic Mechanism Underlying Drug Resistance in Genotype 3 Hepatitis C NS3/4A Protease.

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http://www.wikidata.org/entity/Q39500905

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2016 nî lūn-bûn

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2016年の論文

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2016年学术文章

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2016年学术文章

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2016年学术文章

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2016年学术文章

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2016年学术文章

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2016年學術文章

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2016年學術文章

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2016年學術文章

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name

Molecular and Dynamic Mechanis ...... 3 Hepatitis C NS3/4A Protease.

@en

Molecular and Dynamic Mechanis ...... 3 Hepatitis C NS3/4A Protease.

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type

Item

label

Molecular and Dynamic Mechanis ...... 3 Hepatitis C NS3/4A Protease.

@en

Molecular and Dynamic Mechanis ...... 3 Hepatitis C NS3/4A Protease.

@nl

prefLabel

Molecular and Dynamic Mechanis ...... 3 Hepatitis C NS3/4A Protease.

@en

Molecular and Dynamic Mechanis ...... 3 Hepatitis C NS3/4A Protease.

@nl

P1476

Molecular and Dynamic Mechanis ...... 3 Hepatitis C NS3/4A Protease.

@en

P2093

Akbar Ali

http://www.w3.org/2001/XMLSchema#string

Celia A Schiffer

http://www.w3.org/2001/XMLSchema#string

Djadé I Soumana

http://www.w3.org/2001/XMLSchema#string

Kristina L Prachanronarong

http://www.w3.org/2001/XMLSchema#string

P2860

IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction

MolProbity: all-atom structure validation for macromolecular crystallography

PHENIX: a comprehensive Python-based system for macromolecular structure solution

Processing of X-ray diffraction data collected in oscillation mode

Global epidemiology and genotype distribution of the hepatitis C virus infection

Preclinical profile of VX-950, a potent, selective, and orally bioavailable inhibitor of hepatitis C virus NS3-4A serine protease

SCH 503034, a mechanism-based inhibitor of hepatitis C virus NS3 protease, suppresses polyprotein maturation and enhances the antiviral activity of alpha interferon in replicon cells.

Construction, expression, and characterization of a novel fully activated recombinant single-chain hepatitis C virus protease

Molecular views of viral polyprotein processing revealed by the crystal structure of the hepatitis C virus bifunctional protease-helicase

Discovery of the HCV NS3/4A protease inhibitor (1R,5S)-N-[3-amino-1-(cyclobutylmethyl)-2,3-dioxopropyl]-3- [2(S)-[[[(1,1-dimethylethyl)amino]carbonyl]amino]-3,3-dimethyl-1-oxobutyl]- 6,6-dimethyl-3-azabicyclo[3.1.0]hexan-2(S)-carboxamide (Sch 503034

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11850-11859

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scholarly article

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10.1021/JACS.6B06454

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English

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138

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Nese Kurt Yilmaz

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2016-08-11T00:00:00Z

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P698

27512818

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5221612

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Molecular and Dynamic Mechanism Underlying Drug Resistance in Genotype 3 Hepatitis C NS3/4A Protease.

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P2860

P2860

Molecular and Dynamic Mechanism Underlying Drug Resistance in Genotype 3 Hepatitis C NS3/4A Protease.

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P50

P577

P698

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P50

P577

P698

P932