The orexin OX(1) receptor exists predominantly as a homodimer in the basal state: potential regulation of receptor organization by both agonist and antagonist ligands.
about
OX1 and OX2 orexin/hypocretin receptor pharmacogeneticsMethods used to study the oligomeric structure of G-protein-coupled receptors.Orexin A suppresses the growth of rat C6 glioma cells via a caspase-dependent mechanism.The prevalence, maintenance, and relevance of G protein-coupled receptor oligomerizationOrexin/hypocretin receptor signalling cascades.Orexin/hypocretin based pharmacotherapies for the treatment of addiction: DORA or SORA?Heteromultimerization of cannabinoid CB(1) receptor and orexin OX(1) receptor generates a unique complex in which both protomers are regulated by orexin A.Intramolecular fluorescence resonance energy transfer (FRET) sensors of the orexin OX1 and OX2 receptors identify slow kinetics of agonist activation.Calcium affects OX1 orexin (hypocretin) receptor responses by modifying both orexin binding and the signal transduction machinery.Orexin Receptor Multimerization versus Functional Interactions: Neuropharmacological Implications for Opioid and Cannabinoid Signalling and Pharmacogenetics.Orexin/Hypocretin Signaling.The Class-A GPCR Dopamine D2 Receptor Forms Transient Dimers Stabilized by Agonists: Detection by Single-Molecule Tracking.
P2860
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P2860
The orexin OX(1) receptor exists predominantly as a homodimer in the basal state: potential regulation of receptor organization by both agonist and antagonist ligands.
description
2011 nî lūn-bûn
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2011年の論文
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2011年学术文章
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2011年学术文章
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2011年学术文章
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2011年学术文章
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2011年学术文章
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2011年學術文章
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2011年學術文章
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2011年學術文章
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name
The orexin OX
@nl
The orexin OX(1) receptor exis ...... gonist and antagonist ligands.
@en
type
label
The orexin OX
@nl
The orexin OX(1) receptor exis ...... gonist and antagonist ligands.
@en
prefLabel
The orexin OX
@nl
The orexin OX(1) receptor exis ...... gonist and antagonist ligands.
@en
P2093
P2860
P356
P1433
P1476
The orexin OX(1) receptor exis ...... agonist and antagonist ligands
@en
P2093
Graeme Milligan
Richard J Ward
Tian-Rui Xu
P2860
P304
P356
10.1042/BJ20110230
P407
P577
2011-10-01T00:00:00Z