Predictive performance for human skin sensitizing potential of the human cell line activation test (h-CLAT).
about
Integrated decision strategies for skin sensitization hazardPrediction of chemical respiratory sensitizers using GARD, a novel in vitro assay based on a genomic biomarker signatureMultivariate Models for Prediction of Human Skin Sensitization HazardPredicting skin sensitizer potency based on in vitro data from KeratinoSens and kinetic peptide binding: global versus domain-based assessment.Test battery with the human cell line activation test, direct peptide reactivity assay and DEREK based on a 139 chemical data set for predicting skin sensitizing potential and potency of chemicals.Dendritic cells and the assessment in vitro of skin sensitizing potential.Non-animal test methods for predicting skin sensitization potentials.Prediction of skin sensitizers using alternative methods to animal experimentation.Prediction of skin sensitization potency using machine learning approaches.State of the art in non-animal approaches for skin sensitization testing: from individual test methods towards testing strategies.Discrimination of skin sensitizers from non-sensitizers by interleukin-1α and interleukin-6 production on cultured human keratinocytes.Systemic drugs inducing non-immediate cutaneous adverse reactions and contact sensitizers evoke similar responses in THP-1 cells.Genomic allergen rapid detection in-house validation--a proof of concept.Xenobiotic metabolizing enzyme activities in cells used for testing skin sensitization in vitro.Reactivity of chemical sensitizers toward amino acids in cellulo plays a role in the activation of the Nrf2-ARE pathway in human monocyte dendritic cells and the THP-1 cell line.Fragrance allergens linalool and limonene allylic hydroperoxides in skin allergy: mechanisms of action focusing on transcription factor Nrf2.
P2860
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P2860
Predictive performance for human skin sensitizing potential of the human cell line activation test (h-CLAT).
description
2011 nî lūn-bûn
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2011年の論文
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2011年学术文章
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2011年学术文章
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2011年学术文章
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2011年学术文章
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2011年學術文章
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name
Predictive performance for hum ...... line activation test (h-CLAT).
@en
Predictive performance for hum ...... uman cell line activation test
@nl
type
label
Predictive performance for hum ...... line activation test (h-CLAT).
@en
Predictive performance for hum ...... uman cell line activation test
@nl
prefLabel
Predictive performance for hum ...... line activation test (h-CLAT).
@en
Predictive performance for hum ...... uman cell line activation test
@nl
P2093
P2860
P1433
P1476
Predictive performance for hum ...... line activation test (h-CLAT).
@en
P2093
Hitoshi Sakaguchi
Hitoshi Sasa
Masaaki Miyazawa
Morihiko Hirota
Nanae Mugita
Naohiro Nishiyama
Sakiko Sono
Takao Ashikaga
Yuichi Ito
Yuko Nukada
P2860
P304
P356
10.1111/J.1600-0536.2011.01952.X
P577
2011-07-18T00:00:00Z