Potent, selective inhibitors of fibroblast growth factor receptor define fibroblast growth factor dependence in preclinical cancer models.

Potent, selective inhibitors of fibroblast growth factor receptor define fibroblast growth factor dependence in preclinical cancer models.

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http://www.wikidata.org/entity/Q39505432
Targeting receptor tyrosine kinases in gastric cancerVirtual screening on an α-helix to β-strand switchable region of the FGFR2 extracellular domain revealed positive and negative modulators.Is fibroblast growth factor receptor 4 a suitable target of cancer therapy?Dovitinib (TKI258), a multi-target angiokinase inhibitor, is effective regardless of KRAS or BRAF mutation status in colorectal cancer.Combinatorial Pharmacophore-Based 3D-QSAR Analysis and Virtual Screening of FGFR1 Inhibitors.Detection, Characterization, and Inhibition of FGFR-TACC Fusions in IDH Wild-type Glioma.Targeted therapy in the management of advanced gastric cancer: are we making progress in the era of personalized medicine?Critical signal transduction pathways in CLL.Role of the tumor microenvironment in the pathogenesis of gastric carcinoma.Approaches targeting the FGF-FGFR system: a review of the recent patent literature and associated advanced therapeutic agents.Lineage-specific biomarkers predict response to FGFR inhibition.Tumour cell responses to new fibroblast growth factor receptor tyrosine kinase inhibitors and identification of a gatekeeper mutation in FGFR3 as a mechanism of acquired resistance.Fragment-Based Discovery of Potent and Selective DDR1/2 Inhibitors.
P2860

Potent, selective inhibitors of fibroblast growth factor receptor define fibroblast growth factor dependence in preclinical cancer models.

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http://www.wikidata.org/entity/Q39505432
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2011 nî lūn-bûn
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2011年の論文
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2011年学术文章
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2011年学术文章
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2011年学术文章
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2011年学术文章
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2011年学术文章
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2011年學術文章
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2011年學術文章
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2011年學術文章
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name
Potent, selective inhibitors o ...... in preclinical cancer models.
@en
Potent, selective inhibitors o ...... in preclinical cancer models.
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type
label
Potent, selective inhibitors o ...... in preclinical cancer models.
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Potent, selective inhibitors o ...... in preclinical cancer models.
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prefLabel
Potent, selective inhibitors o ...... in preclinical cancer models.
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Potent, selective inhibitors o ...... in preclinical cancer models.
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P1433
P1476
P2093
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Potent, selective inhibitors o ...... in preclinical cancer models.
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P2093
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10.1158/1535-7163.MCT-11-0426
P433
P478
P577
P698