Domain interactions in the yeast ATP binding cassette transporter Ycf1p: intragenic suppressor analysis of mutations in the nucleotide binding domains
about
Chronic infantile neurological cutaneous and articular syndrome is caused by mutations in CIAS1, a gene highly expressed in polymorphonuclear cells and chondrocytesA region within a lumenal loop of Saccharomyces cerevisiae Ycf1p directs proteolytic processing and substrate specificity.Requirement of the N-terminal extension for vacuolar trafficking and transport activity of yeast Ycf1p, an ATP-binding cassette transporter.Insight in eukaryotic ABC transporter function by mutation analysis.Long-range coupling between the extracellular gates and the intracellular ATP binding domains of multidrug resistance protein pumps and cystic fibrosis transmembrane conductance regulator channelsGenetic basis for in vitro and in vivo resistance to lincosamides, streptogramins A, and pleuromutilins (LSAP phenotype) in Enterococcus faecium.Cooperative assembly and misfolding of CFTR domains in vivo.Efflux-mediated antifungal drug resistance.ABC transporters in Saccharomyces cerevisiae and their interactors: new technology advances the biology of the ABCC (MRP) subfamily.An ATP-binding cassette transporter related to yeast vacuolar ScYCF1 is important for Cd sequestration in Chlamydomonas reinhardtii.Gln-222 in transmembrane domain 4 and Gln-526 in transmembrane domain 9 are critical for substrate recognition in the yeast high affinity glutathione transporter, Hgt1pThe ATP-binding cassette (ABC) transporter Bpt1p mediates vacuolar sequestration of glutathione conjugates in yeast.Ycf1-dependent cadmium detoxification by yeast requires phosphorylation of residues Ser908 and Thr911.Tuning intracellular homeostasis of human uroporphyrinogen III synthase by enzyme engineering at a single hotspot of congenital erythropoietic porphyria.
P2860
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P2860
Domain interactions in the yeast ATP binding cassette transporter Ycf1p: intragenic suppressor analysis of mutations in the nucleotide binding domains
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
2001年论文
@zh
2001年论文
@zh-cn
name
Domain interactions in the yea ...... the nucleotide binding domains
@en
Domain interactions in the yea ...... he nucleotide binding domains.
@nl
type
label
Domain interactions in the yea ...... the nucleotide binding domains
@en
Domain interactions in the yea ...... he nucleotide binding domains.
@nl
prefLabel
Domain interactions in the yea ...... the nucleotide binding domains
@en
Domain interactions in the yea ...... he nucleotide binding domains.
@nl
P2093
P2860
P1476
Domain interactions in the yea ...... the nucleotide binding domains
@en
P2093
M Martínez-Burgos
P2860
P304
P356
10.1128/JB.183.16.4761-4770.2001
P407
P577
2001-08-01T00:00:00Z