Mechanism of poly(A) signal transduction to RNA polymerase II in vitro.
about
Human TRiC complex purified from HeLa cells contains all eight CCT subunits and is active in vitroYhh1p/Cft1p directly links poly(A) site recognition and RNA polymerase II transcription terminationPoly(A) signal-dependent degradation of unprocessed nascent transcripts accompanies poly(A) signal-dependent transcriptional pausing in vitroTorpedo Nuclease Rat1 Is Insufficient to Terminate RNA Polymerase II in VitroFunctions for S. cerevisiae Swd2p in 3' end formation of specific mRNAs and snoRNAs and global histone 3 lysine 4 methylation.Independent functions of yeast Pcf11p in pre-mRNA 3' end processing and in transcription termination.Npl3 is an antagonist of mRNA 3' end formation by RNA polymerase II.Functional interactions between the transcription and mRNA 3' end processing machineries mediated by Ssu72 and Sub1Transitions in RNA polymerase II elongation complexes at the 3' ends of genesThe poly(A)-dependent transcriptional pause is mediated by CPSF acting on the body of the polymerase.Coupled RNA polymerase II transcription and 3' end formation with yeast whole-cell extracts.RNA polymerase II pausing downstream of core histone genes is different from genes producing polyadenylated transcripts.Identification of cis elements directing termination of yeast nonpolyadenylated snoRNA transcripts.The role of the yeast cleavage and polyadenylation factor subunit Ydh1p/Cft2p in pre-mRNA 3'-end formationPolyadenylation releases mRNA from RNA polymerase II in a process that is licensed by splicing.The conserved AAUAAA hexamer of the poly(A) signal can act alone to trigger a stable decrease in RNA polymerase II transcription velocity.Functional coupling of last-intron splicing and 3'-end processing to transcription in vitro: the poly(A) signal couples to splicing before committing to cleavage.Strong polyadenylation and weak pausing combine to cause efficient termination of transcription in the human Ggamma-globin gene.GRS1, a yeast tRNA synthetase with a role in mRNA 3' end formation.Poly(A)-dependent transcription termination: continued communication of the poly(A) signal with the polymerase is required long after extrusion in vivo.The poly(A) signal, without the assistance of any downstream element, directs RNA polymerase II to pause in vivo and then to release stochastically from the template.Analysis of polymerase II elongation complexes by native gel electrophoresis. Evidence for a novel carboxyl-terminal domain-mediated termination mechanism.
P2860
Q24299586-7D180381-F982-4A40-9343-03D9120DDFF1Q24534246-5B7A7D64-4B12-44E0-ADAF-99FC17995578Q24650853-E2CDADBF-590F-4857-A9DB-D1CE7781C164Q27656021-5F1ECAF8-44E7-4D94-8866-8F1447092D4DQ27930951-22707BBD-C433-418A-A411-294A6BCA769DQ27933119-64017B84-1103-4E98-BCCF-F0C35891C809Q27935622-4460E62B-CE0C-4CB3-9CC8-66B475AA4D09Q27939095-BE0BEE19-1D3D-4D32-80CB-E2C4689C6029Q29614767-E2D636DF-929E-4EFD-A1E1-28E71033E8FFQ34004722-60D1E63D-D169-46E2-9ED2-27E4C6A7BEB6Q34210432-28ABCABB-D8DF-4AEB-88B0-CC604F6235DEQ34305741-5552AA7B-B4D9-4077-A0D0-53DE4C4614F2Q34330195-65CACC6C-0119-44BB-B3E3-3F66BFD5D01CQ35186139-1E8633DB-B010-4144-BE06-2917493D6208Q37168944-2D7CDCFF-3458-49AD-8C36-51757DE18610Q41875673-54CF5136-0BB8-421F-97E5-EF1B39918DA1Q41911100-6B25EBB2-C73C-46BB-A5C5-474ED4053E88Q42104053-F15D3D47-2857-4983-99D6-F9FF11FC490AQ44509758-9E9005DA-94B1-4A61-A6DB-2130787A27A5Q46231341-392D2451-31ED-4BCE-8A89-D2BBFFAF52DBQ46370210-5EF66920-AA5C-4EFB-AEF0-3C3514CBD0A2Q47070721-E4E03FD4-B926-432C-9C81-091B8C6CDAB8
P2860
Mechanism of poly(A) signal transduction to RNA polymerase II in vitro.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
2001年论文
@zh
2001年论文
@zh-cn
name
Mechanism of poly
@nl
Mechanism of poly(A) signal transduction to RNA polymerase II in vitro.
@en
type
label
Mechanism of poly
@nl
Mechanism of poly(A) signal transduction to RNA polymerase II in vitro.
@en
prefLabel
Mechanism of poly
@nl
Mechanism of poly(A) signal transduction to RNA polymerase II in vitro.
@en
P2093
P2860
P1476
Mechanism of poly(A) signal transduction to RNA polymerase II in vitro.
@en
P2093
P2860
P304
P356
10.1128/MCB.21.21.7495-7508.2001
P407
P577
2001-11-01T00:00:00Z