Anthracyclines disrupt telomere maintenance by telomerase through inducing PinX1 ubiquitination and degradation.
about
PinX1 is involved in telomerase recruitment and regulates telomerase function by mediating its localizationTherapeutic Targeting of TelomeraseFerritin heavy chain in triple negative breast cancer: a favorable prognostic marker that relates to a cluster of differentiation 8 positive (CD8+) effector T-cell response.The telomere/telomerase binding factor PinX1 is a new target to improve the radiotherapy effect of oesophageal squamous cell carcinomas.Gene expression levels of human shelterin complex and shelterin-associated factors regulated by the topoisomerase II inhibitors doxorubicin and etoposide in human cultured cells.Preanalytical Conditions and DNA Isolation Methods Affect Telomere Length Quantification in Whole Blood.PinX1 is up-regulated and associated with poor patients' survival in gliomasTherapeutically targeting glypican-3 via a conformation-specific single-domain antibody in hepatocellular carcinoma.PinX1 suppresses tumorigenesis by negatively regulating telomerase/telomeres in colorectal carcinoma cells and is a promising molecular marker for patient prognosis.The depletion of PinX1 involved in the tumorigenesis of non-small cell lung cancer promotes cell proliferation via p15/cyclin D1 pathway.Generation of a MLL-AF9-specific stem cell model of acute monocytic leukemia.PinX1 inhibits cell proliferation, migration and invasion in glioma cells.Nucleophosmin Interacts with PIN2/TERF1-interacting Telomerase Inhibitor 1 (PinX1) and Attenuates the PinX1 Inhibition on Telomerase Activity.SAP155-mediated c-myc suppressor far-upstream element-binding protein-interacting repressor splicing variants are activated in colon cancer tissues.PinX1 Is a Potential Prognostic Factor for Non-Small-Cell Lung Cancer and Inhibits Cell Proliferation and MigrationKey Immune Cell Cytokines Affects the Telomere Activity of Cord Blood Cells In vitroMolecular Recognition of Parallel G-quadruplex [d-(TTGGGGT)]₄ Containing Telomeric DNA Sequence by Anticancer Drug Daunomycin: NMR-Based Structure and Thermal Stability
P2860
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P2860
Anthracyclines disrupt telomere maintenance by telomerase through inducing PinX1 ubiquitination and degradation.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Anthracyclines disrupt telomer ...... biquitination and degradation.
@en
Anthracyclines disrupt telomer ...... biquitination and degradation.
@nl
type
label
Anthracyclines disrupt telomer ...... biquitination and degradation.
@en
Anthracyclines disrupt telomer ...... biquitination and degradation.
@nl
prefLabel
Anthracyclines disrupt telomer ...... biquitination and degradation.
@en
Anthracyclines disrupt telomer ...... biquitination and degradation.
@nl
P2093
P2860
P356
P1433
P1476
Anthracyclines disrupt telomer ...... biquitination and degradation.
@en
P2093
P2860
P2888
P356
10.1038/ONC.2011.214
P407
P577
2011-06-06T00:00:00Z