Potassium channel silencing by constitutive endocytosis and intracellular sequestration.
about
Crystal structure of the human two-pore domain potassium channel K2P1Oestrogen promotes KCNQ1 potassium channel endocytosis and postendocytic trafficking in colonic epitheliumNew Insights on Astrocyte Ion Channels: Critical for Homeostasis and Neuron-Glia SignalingThe acid-sensitive, anesthetic-activated potassium leak channel, KCNK3, is regulated by 14-3-3β-dependent, protein kinase C (PKC)-mediated endocytic trafficking.Expression of background potassium channels in rat DRG is cell-specific and down-regulated in a neuropathic pain modelOne SUMO is sufficient to silence the dimeric potassium channel K2P1A hydrophobic barrier deep within the inner pore of the TWIK-1 K2P potassium channel.Recombinant tandem of pore-domains in a Weakly Inward rectifying K+ channel 2 (TWIK2) forms active lysosomal channels.The K+ channel KIR2.1 functions in tandem with proton influx to mediate sour taste transduction.Molecular aspects of structure, gating, and physiology of pH-sensitive background K2P and Kir K+-transport channels.Altered and dynamic ion selectivity of K+ channels in cell development and excitabilityTWIK1, a unique background channel with variable ion selectivity.Acid-sensitive TWIK and TASK two-pore domain potassium channels change ion selectivity and become permeable to sodium in extracellular acidificationGenetic Deletion of TREK-1 or TWIK-1/TREK-1 Potassium Channels does not Alter the Basic Electrophysiological Properties of Mature Hippocampal Astrocytes In Situ.Electrophysiological properties of NG2(+) cells: Matching physiological studies with gene expression profiles.Mixing and matching TREK/TRAAK subunits generate heterodimeric K2P channels with unique properties.Silencing of the tandem pore domain halothane-inhibited K+ channel 2 (THIK2) relies on combined intracellular retention and low intrinsic activity at the plasma membrane.The contribution of TWIK-1 channels to astrocyte K(+) current is limited by retention in intracellular compartmentsClassification of 2-pore domain potassium channels based on rectification under quasi-physiological ionic conditions.Targets and consequences of protein SUMOylation in neurons.Trafficking of neuronal two pore domain potassium channels.Molecular physiology of pH-sensitive background K(2P) channels.Silent but not dumb: how cellular trafficking and pore gating modulate expression of TWIK1 and THIK2.Endocytosis as a mode to regulate functional expression of two-pore domain potassium (K₂p) channels.The family of K2P channels: salient structural and functional properties.Much more than a leak: structure and function of K₂p-channels.Ethanol Enhances TGF-β Activity by Recruiting TGF-β Receptors From Intracellular Vesicles/Lipid Rafts/Caveolae to Non-Lipid Raft Microdomains.Breaking the silence: functional expression of the two-pore-domain potassium channel THIK-2.CK2 phosphorylation of an acidic Ser/Thr di-isoleucine motif in the Na+/H+ exchanger NHE5 isoform promotes association with beta-arrestin2 and endocytosis.Exploring the Dynamics of the TWIK-1 Channel.Silent TWIK-1 potassium channels conduct monovalent cation currents.mGluR3 Activation Recruits Cytoplasmic TWIK-1 Channels to Membrane that Enhances Ammonium Uptake in Hippocampal Astrocytes.Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK)Emerging Roles of TWIK-1 Heterodimerization in the Brain.Astroglial transcriptome dysregulation in early disease of an ALS mutant SOD1 mouse model.Activation of tandem pore domain in a weak inwardly rectifying K+ channelsTWIK-1/TASK-3 heterodimeric channels contribute to the neurotensin-mediated excitation of hippocampal dentate gyrus granule cells
P2860
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P2860
Potassium channel silencing by constitutive endocytosis and intracellular sequestration.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
2009年论文
@zh
2009年论文
@zh-cn
name
Potassium channel silencing by constitutive endocytosis and intracellular sequestration.
@en
Potassium channel silencing by constitutive endocytosis and intracellular sequestration.
@nl
type
label
Potassium channel silencing by constitutive endocytosis and intracellular sequestration.
@en
Potassium channel silencing by constitutive endocytosis and intracellular sequestration.
@nl
prefLabel
Potassium channel silencing by constitutive endocytosis and intracellular sequestration.
@en
Potassium channel silencing by constitutive endocytosis and intracellular sequestration.
@nl
P2093
P2860
P50
P356
P1476
Potassium channel silencing by constitutive endocytosis and intracellular sequestration
@en
P2093
Jacques Barhanin
Magalie P Tardy
Saïd Bendahhou
P2860
P304
P356
10.1074/JBC.M109.078535
P407
P577
2009-12-03T00:00:00Z