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The tyrosine kinase Lck is a positive regulator of the mitochondrial apoptosis pathway by controlling Bak expressionCellular disorganization and extensive apoptosis in the developing heart of mice that lack cardiac muscle alpha-actin: apparent cause of perinatal deathExpression of kinase-defective mutants of c-Src in human metastatic colon cancer cells decreases Bcl-xL and increases oxaliplatin- and Fas-induced apoptosis.The C terminus of c-Src inhibits breast tumor cell growth by a kinase-independent mechanism.Cellular processes of v-Src transformation revealed by gene profiling of primary cells--implications for human cancer.Stat3-mediated Myc expression is required for Src transformation and PDGF-induced mitogenesis.Shear stress induces cell apoptosis via a c-Src-phospholipase D-mTOR signaling pathway in cultured podocytes.Mouse mammary tumor virus suppresses apoptosis of mammary epithelial cells through ITAM-mediated signaling.v-Src Causes Chromosome Bridges in a Caffeine-Sensitive Manner by Generating DNA DamageA common signaling cascade may underlie "addiction" to the Src, BCR-ABL, and EGF receptor oncogenes.Cytokinesis Failure Leading to Chromosome Instability in v-Src-Induced Oncogenesis.Src tyrosine kinase inhibits apoptosis through the Erk1/2- dependent degradation of the death accelerator Bik.Pleiotropic action of AP-1 in v-Src-transformed cells.Atypical protein kinase C activity is required for extracellular matrix degradation and invasion by Src-transformed cellsSRC-mediated phosphorylation of focal adhesion kinase couples actin and adhesion dynamics to survival signalingDiffering Src signaling levels have distinct outcomes in Drosophila.Src protein tyrosine kinases in stress responsesNovel β-phenylacrylic acid derivatives exert anti-cancer activity by inducing Src-mediated apoptosis in wild-type KRAS colon cancer
P2860
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P2860
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
2000年论文
@zh
2000年论文
@zh-cn
name
v-Src generates a p53-independent apoptotic signal.
@en
v-Src generates a p53-independent apoptotic signal.
@nl
type
label
v-Src generates a p53-independent apoptotic signal.
@en
v-Src generates a p53-independent apoptotic signal.
@nl
prefLabel
v-Src generates a p53-independent apoptotic signal.
@en
v-Src generates a p53-independent apoptotic signal.
@nl
P2093
P2860
P1476
v-Src generates a p53-independent apoptotic signal.
@en
P2093
P2860
P304
P356
10.1128/MCB.20.24.9271-9280.2000
P407
P577
2000-12-01T00:00:00Z