Reciprocal feedback regulation of PI3K and androgen receptor signaling in PTEN-deficient prostate cancer - Wikidata - wikimedia - TriplyDB

Reciprocal feedback regulation of PI3K and androgen receptor signaling in PTEN-deficient prostate cancer

Reciprocal feedback regulation of PI3K and androgen receptor signaling in PTEN-deficient prostate cancer

http://www.wikidata.org/entity/Q39541646

about

Resistance to Novel Antiandrogen Therapies in Metastatic Castration-Resistant Prostate Cancer The Androgen Receptor Bridges Stem Cell-Associated Signaling Nodes in Prostate Stem Cells PSA and beyond: alternative prostate cancer biomarkers Persistent androgen receptor addiction in castration-resistant prostate cancer Emerging mechanisms of resistance to androgen receptor inhibitors in prostate cancer Prostate cancer stem cells: the role of androgen and estrogen receptors The associations between Parkinson's disease and cancer: the plot thickens Insights into Chemoresistance of Prostate Cancer Polo-like kinase 1, on the rise from cell cycle regulation to prostate cancer development What a tangled web we weave: emerging resistance mechanisms to inhibition of the phosphoinositide 3-kinase pathway Growth factor and signaling pathways and their relevance to prostate cancer therapeutics Abiraterone in prostate cancer: a new angle to an old problem The mutational landscape of prostate cancer Targeting cancer with kinase inhibitors The many faces of neuroendocrine differentiation in prostate cancer progression Notch signaling in prostate cancer: a moving target Targeting the androgen receptor in prostate and breast cancer: several new agents in development Evolving landscape and novel treatments in metastatic castrate-resistant prostate cancer Quo vadis: advanced prostate cancer-clinical care and clinical research in the era of multiple androgen receptor-directed therapies Turning off AKT: PHLPP as a drug target Translating insights of AR signaling from mouse models Targeting the adaptive molecular landscape of castration-resistant prostate cancer Posttranslational regulation of Akt in human cancer AR-V7 and resistance to enzalutamide and abiraterone in prostate cancer Maximising the potential of AKT inhibitors as anti-cancer treatments The phosphoinositide 3-kinase pathway and therapy resistance in cancer Novel non-AR therapeutic targets in castrate resistant prostate cancer Suppression of survival signalling pathways by the phosphatase PHLPP Modulators of prostate cancer cell proliferation and viability identified by short-hairpin RNA library screening Novel Role for p110β PI 3-Kinase in Male Fertility through Regulation of Androgen Receptor Activity in Sertoli Cells Endothelial Cell mTOR Complex-2 Regulates Sprouting Angiogenesis N-Myc Induces an EZH2-Mediated Transcriptional Program Driving Neuroendocrine Prostate Cancer Targeting PI3K in cancer: impact on tumor cells, their protective stroma, angiogenesis and immunotherapy Prostate cancer progression and metastasis: potential regulatory pathways for therapeutic targeting.Targeted androgen pathway suppression in localized prostate cancer: a pilot study.Genetic profiling to determine risk of relapse-free survival in high-risk localized prostate cancer.Improving Gene-Set Enrichment Analysis of RNA-Seq Data with Small Replicates.Androgen receptor promotes ligand-independent prostate cancer progression through c-Myc upregulation Phospho-kinase profile of triple negative breast cancer and androgen receptor signaling.Androgen synthesis inhibitors in the treatment of castration-resistant prostate cancer.

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P2860

Reciprocal feedback regulation of PI3K and androgen receptor signaling in PTEN-deficient prostate cancer

http://www.wikidata.org/entity/Q39541646

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2011 nî lūn-bûn

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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2011年论文

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2011年论文

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name

Reciprocal feedback regulation ...... PTEN-deficient prostate cancer

@en

Reciprocal feedback regulation ...... TEN-deficient prostate cancer.

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type

label

Reciprocal feedback regulation ...... PTEN-deficient prostate cancer

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Reciprocal feedback regulation ...... TEN-deficient prostate cancer.

@nl

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Reciprocal feedback regulation ...... PTEN-deficient prostate cancer

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Reciprocal feedback regulation ...... TEN-deficient prostate cancer.

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J.CCR.2011.04.008

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Reciprocal feedback regulation ...... PTEN-deficient prostate cancer

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Brett S Carver

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Caren Chapinski

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Carl Le

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Charles L Sawyers

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Haley Hieronymus

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Howard Scher

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Jason Koutcher

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John Wongvipat

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Neal Rosen

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Peter T Scardino

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P2860

Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

The program of androgen-responsive genes in neoplastic prostate epithelium.

Development of a second-generation antiandrogen for treatment of advanced prostate cancer

The PI3K pathway as drug target in human cancer

mTOR complex 2 is required for the development of prostate cancer induced by Pten loss in mice

Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis

From HER2/Neu signal cascade to androgen receptor and its coactivators: a novel pathway by induction of androgen target genes through MAP kinase in prostate cancer cells

Pten dose dictates cancer progression in the prostate

NVP-BEZ235, a dual PI3K/mTOR inhibitor, prevents PI3K signaling and inhibits the growth of cancer cells with activating PI3K mutations.

PHLPP: a phosphatase that directly dephosphorylates Akt, promotes apoptosis, and suppresses tumor growth

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575-586

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10.1016/J.CCR.2011.04.008

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