Loss-of-function genetics in mammalian cells: the p53 tumor suppressor model.
about
Predictive biomarkers in precision medicine and drug development against lung cancerPolycomb CBX7 has a unifying role in cellular lifespanA dual-color fluorescence-based platform to identify selective inhibitors of Akt signalingThe proto-oncogene LRF is under post-transcriptional control of MiR-20a: implications for senescenceCharacterization of the p53 response to oncogene-induced senescence.Avian reovirus p17 and σA act cooperatively to downregulate Akt by suppressing mTORC2 and CDK2/cyclin A2 and upregulating proteasome PSMB6.Immortalization of MEF is characterized by the deregulation of specific miRNAs with potential tumor suppressor activityGaining insights into the codon usage patterns of TP53 gene across eight mammalian speciesTranslational approaches targeting the p53 pathway for anti-cancer therapy.Avian Reovirus Protein p17 Functions as a Nucleoporin Tpr Suppressor Leading to Activation of p53, p21 and PTEN and Inactivation of PI3K/AKT/mTOR and ERK Signaling Pathways.ARF stimulates XPC to trigger nucleotide excision repair by regulating the repressor complex of E2F4.Cellular senescence as a target in cancer control.Senescence bypass in mesenchymal stem cells: a potential pathogenesis and implications of pro-senescence therapy in sarcomas.p38α limits the contribution of MAP17 to cancer progression in breast tumors.Immortalized mouse embryo fibroblasts are resistant to miR-290-induced senescence regardless of p53 status.Cellular senescence bypass screen identifies new putative tumor suppressor genes.MAP17, a ROS-dependent oncogene.S-adenosylhomocysteine hydrolase downregulation contributes to tumorigenesis.Down-regulation of spinophilin in lung tumours contributes to tumourigenesis.Absence of p21WAF1 cooperates with c-myc in bypassing Ras-induced senescence and enhances oncogenic cooperation.
P2860
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P2860
Loss-of-function genetics in mammalian cells: the p53 tumor suppressor model.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
2000年论文
@zh
2000年论文
@zh-cn
name
Loss-of-function genetics in mammalian cells: the p53 tumor suppressor model.
@en
Loss-of-function genetics in mammalian cells: the p53 tumor suppressor model.
@nl
type
label
Loss-of-function genetics in mammalian cells: the p53 tumor suppressor model.
@en
Loss-of-function genetics in mammalian cells: the p53 tumor suppressor model.
@nl
prefLabel
Loss-of-function genetics in mammalian cells: the p53 tumor suppressor model.
@en
Loss-of-function genetics in mammalian cells: the p53 tumor suppressor model.
@nl
P2093
P2860
P356
P1476
Loss-of-function genetics in mammalian cells: the p53 tumor suppressor model.
@en
P2093
P2860
P304
P356
10.1093/NAR/28.11.2234
P407
P577
2000-06-01T00:00:00Z